Public Health
Competitive Technologies, Inc. (NYSE Amex: CTT) announced today that CTT"s pain therapy medical device will be used by clinical investigators at the Virginia Commonwealth University Massey Cancer Center for a Phase II independent clinical study. The study will examine the ability of CTT"s U.S. FDA-cleared device to decrease pain associated with chemotherapy-induced peripheral neuropathy (CIPN).
The criteria used to assess blood alcohol concentrations (BACs) and binge drinking behaviors in children and adolescents should be based on pediatric rather than adult physiology, according to a new University of Pittsburgh study in the June issue of Pediatrics.
Celladon Corporation presented today Phase 1 data from the Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID), a First-in-Human Phase 1/2 Clinical Trial, in a scientific symposium at the 12th Annual American Society of Gene Therapy Meeting.
Enterostomal therapy nurses and people living with an ostomy reported very high levels of satisfaction with a new moldable skin barrier pioneered by ConvaTec Ostomy Care, according to results from a prospective evaluation published this month in the journal Ostomy Wound Management.
Corrupt lifestyles and vices go hand in hand; each feeds the other. But even the worst miscreant needs customary societal amenities to get by. It"s the same with cancer cells. While they rely on vices in the form of genetic mutations to wreak havoc, they must sustain their activity, and that requires equal parts vice and virtue.
Millions of Baby Boomers are struggling to care for their aging parents. Many don"t know where to turn or even what their options are in making important decisions about senior care facilities for their parents.
Several newspapers on Thursday published editorials responding to a Medicare trustees report issued Tuesday that said the trust fund Medicare uses to pay for beneficiaries" hospital care will be insolvent by 2017, two years earlier than predicted by trustees last year. Summaries of the editorials appear below.
Abortion-rights groups on Wednesday offered their support for Supreme Court nominee Judge Sonia Sotomayor but said that they were eager to learn more about her views on abortion rights, an issue on which she has made few major rulings in her time as a judge, the New York Times reports. According to the Times, groups on both sides of the abortion-rights debate tend to believe that Sotomayor would uphold Roe v. Wade because she was nominated by President Obama, who supports abortion rights. However, when asked on Tuesday if Obama questioned Sotomayor about her views on abortion rights before the nomination, White House spokesperson Robert Gibbs said that the president "did not ask that specifically." In addition, none of her rulings has directly dealt with the underlying issues of constitutional privacy that are the foundation for the Roe decision, according to the Times. The abortion-related cases Sotomayor has handled in the past have "turned on other legal issues," rather than privacy, and they have resulted in rulings in favor of abortion-right opponents, the Times reports. For example, in 2002, she wrote an opinion upholding the Bush administration"s "global gag rule" policy banning federal funding of international groups that offer abortion information or services. "The Supreme Court has made clear that the government is free to favor the antiabortion position over the pro-choice position and can do so with public funds," Sotomayor wrote in the opinion. In 2004, she said that antiabortion-rights protesters were permitted to sue police who they claimed used excessive force in stopping a demonstration at a clinic. Sotomayor also has ruled on several immigration cases related to people fighting deportation orders to China over its family planning policies, the Times reports. Because of the limited information on Sotomayor"s abortion-rights views, advocates have stressed that senators ask questions about her views during her confirmation hearing. NARAL Pro-Choice America President Nancy Keenan in a letter to supporters urged them to press senators to ask Sotomayor about privacy rights. Keenan wrote, "Discussion about [Roe] will -- and must -- be part of this nomination process. As you know, choice hangs in the balance on the Supreme Court as the last two major choice-related cases were decided by a 5-to-4 margin" (Savage, New York Times, 5/28). Nancy Northup, president of the Center for Reproductive Rights, said that she would be surprised if an Obama nominee did not support abortion rights but added that "other presidents have been surprised before" when their nominees" views did not align with their assumptions. Northup said that "no one has been able to give us an assurance" of Sotomayor"s views on abortion rights, adding that she would be "very concerned if the question is not asked and answered during the Senate hearings." Feminist Majority Foundation President Eleanor Smeal said, "What we know about [Sotomayor] we like, but I don"t know that answer on abortion rights" (Savage/Nicholas, Los Angeles Times, 5/28). The New York Times reports that more about Sotomayor"s views on abortion rights could come to light if a past writing on the subject surfaces, as was the case during Justice Samuel Alito"s confirmation process. Steven Waldman, editor in chief of beliefnet.com, said, "Everyone is just assuming that because Obama appointed her, she must be a die-hard pro-choice activist, but it"s really quite amazing how little we know about her views on abortion" (Savage, New York Times, 5/28). Thomas Goldstein, a leading appellate attorney and founder of scotusblog.com, said that the "fact that she hasn"t gone off on these sorts of questions" on contentious topics like abortion rights and gay marriage, "I think shows that honestly she"s not a dyed in the wool liberal." He added that there are issues on which Sotomayor could prove to be more conservative than retiring Justice David Souter (Lerer, Politico, 5/27).According to the Washington Post, many antiabortion-rights supporters are critic
Low vitamin D levels in blacks could contribute to health gaps between white and black U.S. residents, Michael Holick, a professor at Boston University and a vitamin D researcher, said recently, the GNS/Chicago Sun-Times reports. According to Holick, blacks have lower levels of vitamin D than whites in part because the higher amount of pigment in their skin makes it harder for their body to absorb the nutrient, which is produced in response to sun exposure. Although scientists are debating optimum vitamin D levels, some scientists have said that vitamin D can reduce the risk of cancer, diabetes, heart disease and other illnesses. Holick added that some scientists believe blacks are more likely to have prostate cancer, breast cancer and colon cancer and have more aggressive forms of the cancer because they have lower levels of vitamin D. John Flack, principal investigator at the Center for Urban and African American Health at Wayne State University, said lower vitamin D levels among blacks is "potentially a very important explanation for some of the differences, from hypertension to cancer to heart failure," adding, "The actual proof is not there, but it"s plausible." Flack added that many factors -- including decreased access to health care and differences in income and education -- contribute to the overall poorer health among blacks. The Institute of Medicine next year is expected to release new guidelines on recommended daily intake for vitamin D. "All Americans, but particularly people with darker skin, should pay attention" to the new guidelines, according to Adit Ginde, a researcher at the University of Colorado Denver School of Medicine who led a recent study that found vitamin D levels are decreasing in all racial groups and are particularly low in blacks (Painter, GNS/Chicago Sun-Times, 5/28).
Mice carrying a "humanized version" of a gene believed to influence speech and language may not actually talk, but they nonetheless do have a lot to say about our evolutionary past, according to a report in the May 29th issue of the journal Cell, a Cell Press publication.
RAJ Devices, the regulatory affairs journal published by Informa and covering the medical technology industry, has published a comprehensive feature on how companies in the US can comply with a much stricter code of ethics that medical technology industry association AdvaMed will launch on 1 July.
Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have uncovered a remarkable property of the contractile ring, a structure required for cell division. Understanding how the contractile ring works to divide the cell may facilitate development of therapies to prevent uncontrolled cell division in cancer.
A dog born with a deadly disease that prevents the body from using stored sugar has survived 20 months and is still healthy after receiving gene therapy at the University of Florida - putting scientists a step closer to finding a cure for the disorder in children.
Researchers based in Gabon and France report the discovery of a new
A new study appearing in Congestive Heart Failure has found that the presence of anemia in patients with chronic heart failure is associated with a significantly increased risk of death. The findings also show that anemia is associated with a poorer degree of left ventricular function and a lower left ventricular ejection fraction, an objective measure of cardiac function.
Two new studies address donor factors that could affect outcomes for liver transplant recipients, particularly those with chronic hepatitis C (HCV). One found that donor steatosis, or fat in the liver, does not affect liver disease progression or three-year survival in recipients with or without HCV. However, transplants from people higher on the Donor Risk Index did adversely affect the outcomes of HCV-positive recipients more than recipients without HCV.
President Barack Obama and Energy Secretary Steve Chu are consistent in their message that when it comes to transportation fuels, carbon-neutral biofuels as an alternative to gasoline are coming. While the focus of a shift from gasoline to biofuels has been on global warming, such a shift could also impact human health. A grant from the Energy Biosciences Institute (EBI) has produced a novel and comprehensive "Life Cycle Impact Assessment" to measure the benefits on human health that might result from a switch to biofuels. Although there are a number of uncertainties that must be addressed for a more accurate picture, these early results show that a biofuel eliminating even 10-percent of current gasoline pollutant emissions would have a substantial impact on human health in this country, especially in urban areas.
Summer isn"t any fun when you have a headache. But for many of the 30 million Americans who suffer from migraine headaches, solutions for soothing headache symptoms may be just around the corner.
The European Medicines Agency has been formally notified by BioPartners GmbH of its decision to withdraw its application for Biferonex (interferon beta-1a), 6 million-international-unit solution for injection, prefilled syringes for subcutaneous administration.
Laughter is not only an effective stress-reliever, but can be heart-healthy, according to research presented at the American College of Sports Medicine"s 56th Annual Meeting in Seattle. Two separate studies examined the role of a good laugh as it relates to health.
Genomic Health, Inc. (Nasdaq: GHDX) today announced results from a study which summarized the gene signatures identified by the Oncotype DX(R) breast cancer test in a large number of male patients for whom the test was used to guide treatment with chemotherapy. The results, which will be presented in a poster presentation on Monday, June 1 (1:00 - 5:00 p.m. ET) at the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, demonstrated that breast cancer in men displays similar gene signatures to female breast cancer.
Congressman James McGovern, D-Massachusetts, has announced National Institutes of Health (NIH) awards for two researchers at Worcester Polytechnic Institute"s Life Sciences and Bioengineering Center at Gateway Park.
CAFFEINE SHOWN AS EFFECTIVE AT REDUCING EXERCISE-INDUCED ASTHMA SYMPTOMS AS AN ALBUTEROL INHALER
The twin epidemics of obesity and type 2 diabetes will continue to fuel an explosion in heart failure, already the world"s most prevalent chronic cardiovascular disease, according to John McMurray, professor of cardiology at the Western Infirmary, Glasgow, and President of the Heart Failure Association. He reported that around one-third of patients with heart failure have evidence of diabetes, and for them the outlook is very serious. For doctors, he added, effective treatment is "very difficult".
Theta oscillations are a type of prominent brain rhythm that orchestrates neuronal activity in the hippocampus, a brain area critical for the formation of new memories. For several decades these oscillations were believed to be "in sync" across the hippocampus, timing the firing of neurons like a sort of central pacemaker. A new study conducted by researchers at the California Institute of Technology (Caltech) argues that this long-held assumption needs to be revised. In a paper published in this week"s issue of the journal Nature, the researchers showed that instead of being in sync, theta oscillations actually sweep along the length of the hippocampus as traveling waves.
"Blog Watch" offers readers a roundup of health policy-related blog posts.Bloggers are tentatively reacting to a report and blog post released by the Congressional Budget Office that summarizes the agency"s approach to estimating the cost of any health overhaul bills. At issue is how CBO will count different stipulations of legislation -- like an individual mandate or a public plan -- and whether their conclusions will result in a heftier price tag. Douglas Elmendorf explained on the Director"s Blog: "In CBO"s view, the key consideration is whether a proposal would be making health insurance an essentially governmental program, tightly controlled by the federal government with little choice available to those who offer and buy health insurance -- or whether the system would provide significant flexibility in terms of the types, prices, and number of private-sector sellers of insurance available to people. The former -- a governmental program -- belongs in the federal budget (including all premiums paid by individuals and firms to private insurers), but the latter -- a largely private-sector system -- does not." Janet Adamy of the Wall Street Journal"s Washington Wire notes that the report doesn"t address the cost estimates of the scenarios. Alan Katz on his Health Care Reform Blog concludes, "the message is clear: the looser government"s hand grips the new health care system the smaller its budgetary impact." Liberal bloggers had a variety of reactions -- some found the report too vague, while others saw it as good news. The New Republic"s Jonathan Cohn says, "you may need a Talmudic scholar to figure out what those implications are." Cohn continues, "Other passages in the briefing are [similarly] vexing and, for what it"s worth, the reactions I"ve gotten from insiders familiar with the report have ranged from sighs of relief to statements not suitable for a family blog." Ezra Klein agrees the report lacks specificity, but says, "Even so, I"m cheered by the simple existence of this ruling. The fact that CBO is explaining its thinking before legislation arrives [is] yet more evidence that CBO appears, insofar as it can, to be trying to help out on health reform. ... That"s an important change from past years." Interesting Elsewhere:
USA Today: It is "gratifying" that Republicans last week introduced a health care proposal because "the simple fact that it exists might improve chances" for bipartisan negotiations, a USA Today editorial states. According to the editorial, the plan -- which would replace the current tax exemption of employer-provided insurance with a refundable tax credit for all families and individuals, regardless of their employment status -- is "no cure-all," but is a "serious proposal that merits serious consideration." The editorial states, "For all those who say the Republican Party is out of ideas, on the issue of health coverage, at least, its proposal is bolder than what the Democrats have offered." However, the editorial notes that both Republicans and Democrats "have identified more groundbreaking ideas, and they are not entirely incompatible." The editorial concludes, "[L]et the debate begin. The only unacceptable approach is the status quo" (USA Today, 5/29).
The Thai AIDS Treatment Action Group recently called on the country to launch a comprehensive harm reduction program for injection drug users in an effort to help curb the spread of HIV, Thailand"s The Nation reports. According to the group, many IDUs are unable to access drug treatment and substation therapy because of the stigma surrounding drug use in the country. Karyn Kaplan, director of development and policy for the group, said, "Health care workers have denied many injecting drug users access to an antiviral drug and the use of methadone." Public Health Minister Witthaya Kaewparadai recently announced that the country"s harm reduction programs have helped to curb the spread of HIV among IDUs, adding that local substitution programs have reduced the number of HIV-positive IDUs and that the country needs increased support from UNAIDS for such efforts. TTAG called for the government to provide prevention and treatment options, such as substitution therapy and needle-exchange programs. The Nation reports that methadone treatment is offered at hospitals across the country as part of the national health care scheme, but many health care workers refuse to administer treatment. In addition, government treatment is offered for 45 days. Kaplan said that the government should revise its policy regarding treatment access for IDUs, as a majority of IDUs are incarcerated and living with HIV or hepatitis-C without treatment access. She called on the government to "implement the international standards of medical treatment for [IDUs], without discrimination and human rights violations" (The Nation, 5/27).
On Tuesday, May 26, 2009, the American Association of Kidney Patients" (AAKP) Executive Director Kim Buettner and members of the AAKP Board of Directors met with staff members of the Centers for Medicare and Medicaid Services (CMS) regarding the passage of the Medicare Improvement for Patients and Providers Act (MIPPA) on chronic kidney disease (CKD) education. MIPPA provides for Medicare coverage of up to six sessions of education for individuals with CKD in stage 4. The education includes instructions on the management of co-morbidities, with the goal of delaying the need for dialysis and discussion on the treatment options available to patients for renal replacement therapy.
Results from a clinical study published today in the New England Journal of Medicine reveal that ablative therapy using the HALO system (BARRX Medical, Inc.) is highly effective for complete eradication of a pre-cancerous condition of the esophagus called Barrett"s esophagus afflicting more than 3.3 million Americans. Additionally, ablative therapy using the HALO system reduced the risk of progression to cancer in the highest risk cohort studied (compared to control) from 19.0% to 2.4%.
The British Thyroid Association (BTA) has organised a survey of 14-15 year old girls in the UK to assess levels of iodine in their diet. Iodine is an essential component of thyroid hormones which help to control the body"s metabolism. Iodine deficiency has substantial effects on growth and development and is a leading cause of preventable mental retardation worldwide. Concern has recently been expressed over the UK iodine status, which has led the BTA and the British Thyroid Foundation, with generous financial support from the Clinical Endocrinology Trust, to carry out this study to assess iodine levels in young females throughout the UK.
Interventional radiology is a dynamic and innovative specialty. In the last ten years new image guided therapies for uterine myomata, infertility, pelvic pain, osteoporosis, and varicose veins have largely been developed. Interventional Radiology in Women"s Health, published by Thieme, focuses on women"s health and the expanding role of interventional radiology within this pioneering area of medicine.
Thieme Publishing Group is pleased to announce the launch of Pharmaceutical Substances Version 3.2. Available via Thieme-connect, Pharmaceutical Substances is a comprehensive reference guide to every significant pharmaceutical compound and includes all FDA approved active pharmaceutical ingredients (APIs).
The Regulatory Affairs Professionals Society (RAPS), the world"s largest
Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic imaging, announces that it has completed patient enrollment of CaRES (Contrast Echocardiography REgistry for Safety Surveillance), the first, multicenter Phase IV observational registry that evaluates the use of ultrasound imaging agents in routine clinical practice. The 1,060 patients who were enrolled at 15 sites in the U.S. were 18 years old or older and required DEFINITY® Vial for (Perflutren Lipid Microsphere) injectable suspension-enhanced echocardiography because of a previous suboptimal, unenhanced echocardiogram.
A new national campaign aiming to reduce the number of undiagnosed heart conditions will visit 12 destinations in England throughout May and June. The CRY Philips Test My Heart Tour 09 is the first free tour of its kind in England and has been made possible by charity CRY, health and well-being company Philips, through the fundraising efforts of families whose lives have been affected by Sudden Death Syndrome (SDS) or Sudden Cardiac Death (SCD), and the Gwyneth Forrester Trust. The tour aims to test over 3,000 14-35 year olds hearts to identify heart conditions which could potentially prove fatal if left untreated. To book a free appointment at one of the 12 tour locations simply go to http://www.testmyheart.org
Detailed data from a randomized Phase 2 study with PROSTVAC(TM) were presented Saturday at the ASCO Annual Meeting in Orlando. The presentation was made by Philip Kantoff MD, Professor of Medicine, Harvard Medical School, and the Dana-Farber Cancer Institute who is also the principal investigator of the study.
People with the spine disease called degenerative spondylolisthesis -- who choose surgical treatment -- experience substantially greater relief from pain over time compared to those who do not have surgery, according to a study published in the June 2009 issue of The Journal of Bone and Joint Surgery (JBJS). In the past, physicians had been uncertain whether surgery provided significantly greater relief for patients, but these results help to confirm the advantages to surgery.
Physicians who treat patients with multiple health problems will fare well under pay-for-performance, which bases physician reimbursement on the quality of care provided, said researchers at Baylor College of Medicine and the Michael E. DeBakey Veterans Affairs Medical Center in Houston in a report in the current issue of the journal Circulation.
Linking genetic material microRNAs with cells that regulate the immune system could one day lead to new therapies for treating cancer, infections and autoimmune diseases, according to a Henry Ford Hospital study.
The March of Washingtons - the first broad-based campaign to increase access
Gene therapy should be used in tandem with stem cell therapy to enhance the reliability of stem cells, provide an opportunity to limit adverse effects and increase treatment success, according to research presented at the American Society of Gene Therapy"s 12th Annual Meeting, May 30.
The four-type (6,11,16,18) human papillomavirus (HPV) vaccine, Gardasil®, has been chosen by the Norwegian authorities for the national vaccination programme after the assessment of a variety of criteria, including efficacy in the prevention of cervical cancer, safety and evidence of long-lasting protection. All available data was considered, including new data presented during the 25th International Papillomavirus Conference (IPC) in May in Malmç¶, Sweden.
Four risk factors that help predict how long men may survive with metastatic prostate cancer could help doctors choose more effective treatments, according to a study led by researchers in the Duke Comprehensive Cancer Center.
Spending hours taking a high-pressure aptitude test may make people feel mentally fatigued, but that fatigue doesn"t necessarily lead to lower test scores, according to new research published by the American Psychological Association. If anything, performance might actually improve on a longer test, the study found.
"Health industry officials delivered a plan to the White House Monday documenting how they"ll attempt to save $2 trillion over a decade through measures like reducing hospitalizations and cutting down on paperwork," the Associated Press reports. "Health insurers, doctors, hospitals, drug-makers and others were under pressure to make good on a pledge they made last month to curb their own costs to help President Barack Obama achieve his health care overhaul goals." Their three big areas of savings: $150 billion to $180 billion would come from more efficient use of health care services, $350 billion to $850 billion from better management of chronic diseases, and $500 billion to $700 billion through administrative improvements such as standardizing claim forms (Werner, 6/1).
The Wall Street Journal reports that "the federal government is stepping up efforts to improve the quality of nursing-home care and now has an online tool consumers can use in evaluating facilities. The Centers for Medicare and Medicaid Services, or CMS, will begin a pilot program this summer to see if cash incentives to nursing homes can improve the care they provide, especially in areas such as nurse staffing and preventable hospitalizations."
The New York Times reports on a series of deep budget cuts to help California, which is some $24 billion in the red, deal with its" ongoing financial woes.
In a new study, young children and their adult caregivers uttered fewer vocalizations, used fewer words and engaged in fewer conversations when in the presence of audible television. The population-based study is the first of its kind completed in the home environment, guided by lead researcher Dimitri A. Christakis, MD, MPH, director of the Center for Child Health, Behavior and Development at Seattle Children"s Research Institute and professor of pediatrics at the University of Washington School of Medicine. "Audible Television and Decreased Adult Words, Infant Vocalizations, and Conversational Turns" was published in the June 2009 issue of Archives of Pediatrics & Adolescent Medicine.
Argos Therapeutics announced the presentation of new information on its soluble CD83 (sCD83) protein program in a poster session at the 2009 American Transplant Congress, held May 30-June 3 in Boston. The poster presentation, to be made on June 2 at 5:30pm by Argos" collaborating scientists from the University of Western Ontario, demonstrates that combination therapy with sCD83 can prolong kidney allograft survival in an animal model of transplantation, and that sCD83 attenuates pathological changes in kidney allografts, induces generation of T regulatory cells and inhibits dendritic cell maturation, all of which may contribute to immunosuppression and allograft tolerance.
A team of University of Minnesota-Twin Cities students from a civil engineering class will head to India later this month to share their ideas and plans for helping bring clean water to thousands of residents living in the slums of Mumbai - the same impoverished area that provided the backdrop for the 2009 Oscar Award-winning movie, "Slumdog Millionaire."
Pakistan has obtained international support for its efforts to fight tuberculosis and lower infant and maternal mortality rates, Mir Aijaz Hussain Jakhrani, the health minister, said recently after returning from the 62nd World Health Assembly (WHA), the International News reports.
Patients are a step closer to getting more say over their healthcare services as plans for a national pilot project reach the next stage, the Department of Health announced.
Hyperion Therapeutics, Inc. announced top-line results from a phase I study of HPN-100 in patients with liver cirrhosis. The data were presented as part of the 2009 Digestive Disease Week meeting. The abstract is titled "Pharmacokinetic (PK) and Safety Analyses of a Novel Ammonia-Reducing Agent in Healthy Adults and Patients with Cirrhosis."
Achieving a world first, scientists in China have induced cells from pigs to become pluripotent stem cells, which like embryonic stem cells are
Pennsylvania and Illinois are expanding health insurance options for for young adults.
New research from the UC Davis Center for
A probable case of swine flu in Wales has been identified by microbiology testing.
A blood-pressure medicine has been shown to reverse the effects of early-stage liver failure in some patients.
Two opinion pieces recently responded to criticisms of Judge Sonia Sotomayor, President Obama"s nominee to the Supreme Court.~ Raina Kelley, Newsweek: The "discussions about whether ... Sotomayor was chosen just because she is a Hispanic woman drive me nuts," Newsweek columnist Kelley writes. She continues, "Yes, the fact that she"s a Latina makes a difference in what she brings to the bench, but let"s not overlook the fact that she"d be qualified for the job even if she were a white man." Citing Sotomayor"s experience as a Second Circuit Court of Appeals judge for more than a decade and her educational qualifications as a graduate of Princeton University and Yale Law School, Kelley writes that "we can assume that she has at least some of the appropriate skills to be a Supreme Court justice." She adds, "But when she sits down for those hearings in front of the cameras and the country, the lingering question will still be, "Did she get into all those great schools just because of her race?"" Kelley writes, "It"s infuriating to me that a woman as competent as Sotomayor will have to prove she deserves her nomination while a white-male colleague with the same resume can skip that step and go straight to his judicial philosophy." According to Kelley, "It is time for our hallowed institutions to look like the country" they serve. She notes that "white males have gotten the jobs over at the Supreme Court 96% of the time," concluding that "the assumption that they"re naturally the best candidate for everything, and we"re doing anyone else a favor if we give them a desirable job, is a bit much" (Kelley, Newsweek, 5/29).~ Kathleen Parker, Washington Post: "Even without the help of all those foot soldiers who blast out late-night memos, any sentient being could have predicted the reaction" last week to the nomination of Sotomayor, syndicated columnist Parker writes. She adds, "Within minutes" of the announcement, "a dozen other e-mails tumbled through the hatch enumerating all the reasons Sotomayor was a terrible pick: affirmative action, identity politics, the Ricci [v. DeStefano] case, double standards, racism, sexism." She continues, "Although her judicial record has raised some legitimate concerns, Sotomayor isn"t so easily characterized as the radical liberal that some on the right have suggested. She has ruled favorably toward abortion protesters and unfavorably toward minority plaintiffs." In reference to Sotomayor"s 2001 comments that her experiences as a Hispanic woman might help her reach a ""better conclusion than a white male who hasn"t lived that life,"" Parker asks, "Could a white man get away with saying something comparable about a Latina? Of course not. After Latinas have run the world for 2,000 years, they won"t be able to say it ever again either." Parker continues, "For now, the hot winds of punditry could use a little chill," concluding, "Calling Sotomayor a sexist and racist, far from being fair, is an irrational rush to judgment unbecoming ladies, gentlemen, scoundrels and scholars" (Parker, Washington Post, 5/31).
The first artificial organ for liver patients that uses immortalized human liver cells, the Extracorporeal Liver Assist Device, or ELAD®, is a bedside system that treats blood plasma, metabolizing toxins and synthesizing proteins just like a real liver does.
Researchers unveiled data during Digestive Disease Week® (DDW®) 2009 examining the potential risks associated with two commonly-used treatments, particularly among the elderly: acid suppressors and antithrombotics. DDW is the largest international gathering of physicians and researchers in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
As America"s drive for healthcare reforms heats up, the lobbying group for health insurers will meet this week in San Diego-and will be greeted by an impassioned demonstration organized by nurses, doctors, and patients supporting single-payer healthcare reforms.
Mice lacking the fat hormone leptin or the ability to respond to it become morbidly obese and severely diabetic - not to mention downright sluggish. Now, a new study in the June Cell Metabolism shows that blood sugar control in those animals can be completely restored by returning leptin sensitivity to a single class of neurons in the brain, which account for only a small fraction of those that normally carry the hormone receptors.
Violence, sexual abuse, harassment, appalling living conditions, and a serious lack of access to essential healthcare define the desperate lives of thousands of Zimbabweans in South Africa today, warned the international medical humanitarian aid organization, Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF).
Corrected vision impairment could prevent billions of dollars in lost productivity annually, according to a study by researchers from the Johns Hopkins Bloomberg School of School of Public Health, the International Centre for Eyecare Education, the University of New South Wales and the African Vision Research Institute. Researchers estimate that nearly 158 million people globally suffer with vision impairment resulting from uncorrected refractive error, which can usually be eliminated with a pair of eyeglasses and an eye examination. This is the first study to estimate the productivity loss from uncorrected refractive error and is published in the June 2009 issue of the Bulletin of the World Health Organization.
Cephalon, Inc. (Nasdaq: CEPH) today announced that NUVIGIL® (armodafinil) Tablets [C-IV], a longer-lasting formulation of modafinil, is now available. NUVIGIL is indicated to improve wakefulness throughout the day for the millions of patients who struggle with excessive sleepiness associated with treated obstructive sleep apnea, shift work sleep disorder, also known as shift work disorder, and narcolepsy. Cephalon has finalized the commercialization plans for NUVIGIL and, beginning today, any patient with a NUVIGIL prescription should be able to obtain the medication from their pharmacy or have it filled within 24 hours.
A closer look at regulatory and clinical concerns with generic immunosuppression medications in thoracic transplantation is required, according to an educational advisory by the International Society for Heart and Lung Transplantation (ISHLT) in the July 2009 issue of The Journal of Heart and Lung Transplantation, published by Elsevier.
Despite what some may think, people aren"t hiding their use of BOTOX® Cosmetic and hyaluronic acid dermal fillers. In fact, according to survey statistics released today by The Aesthetic Surgery Education & Research Foundation (ASERF), the research arm of the American Society for Aesthetic Plastic Surgery (ASAPS), nearly nine out of 10 respondents (87 percent) openly discuss their BOTOX® Cosmetic and hyaluronic acid dermal filler treatments with others, with seven out of ten (70 percent) receiving support from the people they told.
The BMA is stepping up its activity to publicise its concerns about government reforms that have created a market in healthcare and allowed commercially run firms to provide NHS care.
- 1 confirmed case in Wales (a 31 year old male from the Caerphilly local authority area. He has had mild flu symptoms, has been offered antivirals and is recovering at home).
New research published by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme has found that while ibuprofen and paracetamol is more effective when used together when treating fever in pre-school children, ibuprofen should be used first as this will reduce the temperature quicker.
Leading UK maternity charity, MIDIRS, has launched a new e-update facility designed to assist health care professionals and student midwives with their continuing professional development. Registration to the service is free and available NOW!
Based on the top-level analysis of a Phase II study, EyeGate Pharma announces that EGP-437, a corticosteroid solution administered by a non-invasive ocular drug delivery system, improved signs and symptoms in patients with dry eye syndrome (DES).
Traumatic brain injury - not heart disease, stroke or cancer - is the number one cause of death and disability in people under 45. Each year, some 1.5 million Americans, including soldiers, athletes, the elderly and children, sustain head injuries, and nearly half of them will be hospitalized and treated in an emergency room or intensive care unit.
As projected, Eli Lilly and Company (NYSE: LLY) has resubmitted its supplemental New Drug Application (sNDA) for Cymbalta(R) (duloxetine HCl) for the management of chronic pain to the U.S. Food and Drug Administration (FDA). Lilly"s resubmission is based on a recently completed study in chronic pain due to osteoarthritis, the extension phase of a chronic low back pain study and previously completed studies in pain due to osteoarthritis and chronic low back pain. The application is supported by studies in diabetic peripheral neuropathic pain (DPNP) and fibromyalgia.
In children with the rare disease Pfeiffer syndrome, craniofacial surgery to correct skull defects is followed by a distinct pattern of increases in body temperature, reports a study in the January Journal of Craniofacial Surgery. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, pharmacy and the pharmaceutical industry.
Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place.
Merck"s human papillomavirus vaccine, Gardasil, was 90% effective in preventing infection with the virus and cervical disease in women ages 24 to 45, according to a study published Monday in the medical journal Lancet, Reuters reports (Fox, Reuters, 6/1). In the U.S., the vaccine currently is FDA-approved for girls and women ages nine to 26. Centers for Disease Control and Prevention guidelines recommend routine three-dose vaccination of girls ages 11 and 12 and for girls and women ages 13 to 26 who have not yet been vaccinated (CDC fact sheet, June 2008). It is designed to protect against HPV types 16 and 18, which cause about 70% of all cervical cancer cases, and HPV types 6 and 11, which cause genital warts.The new study, led by Nubia Munoz of the National Institute of Cancer in Bogota, Colombia, and funded by Merck, involved women ages 24 to 45 with no history of cervical disease or genital warts who either received the vaccine or a placebo injection. The study found that women who received the vaccine were significantly less likely to be infected with certain strains of HPV than those who received placebo shots. According to the researchers, four women out of 1,900 who received the vaccine developed HPV or cervical disease after two years, compared with 41 women out of 1,900 in the placebo group.Reuters reports that the results of the study could help Merck as it seeks approval for marketing Gardasil for use in older women. The researchers said in the study that older women might be at risk for HPV infection as "[c]hanges in sexual behavior during the past 30 years ... have led to more widespread premarital sexual intercourse and acquisition of new sexual partners around middle age." They added, "As the potential for HPV infection and disease exists in women in their third, fourth and fifth decades of life, these women could benefit from prophylactic HPV vaccination." According to Reuters, a mathematical model published in October 2005 showed that vaccinating older women could cut rates of cervical cancer in women through age 45 by half. Merck also has released data showing the effectiveness of the vaccine in preventing genital lesions in men.According to the Centers for Disease Control and Prevention, HPV is the most common sexually transmitted infection worldwide, and about 20 million U.S. residents are infected with it. The virus is the leading cause of cervical cancer, which causes about 3,870 deaths in the U.S. and 300,000 deaths globally every year, and it also can cause anal, penile, mouth and neck cancer (Reuters, 6/1).
Some liberal journalists and bloggers are criticizing Fox News host Bill O"Reilly for the language he has used when discussing abortion provider George Tiller, with some suggesting that his harsh rhetoric incites violence, the New York Times reports. Tiller, who was one of a small number of U.S. doctors who performed abortions later in pregnancy, was shot and killed on Sunday while serving as an usher in his local church. On Monday, O"Reilly said that "clear-thinking Americans should condemn" the murder but also defended his past remarks about Tiller. O"Reilly said that "every single thing we said about Tiller was true, and my analysis was based on those facts."Salon within nine hours of Tiller"s death had posted video clips of 29 on-air references that O"Reilly had made about Tiller on past programs. O"Reilly has said that Tiller and other abortion providers conduct the "business of destruction" and that he "wouldn"t want to be these people if there is a Judgment Day." Media Matters for America on its site published a 2006 clip in which O"Reilly said, "If I could get my hands on Tiller," adding, "Well, you know. Can"t be vigilantes. Can"t do that. It"s just a figure of speech."According to the Times, O"Reilly often draws particular attention because his cable news show has held a No. 1 rating for the past seven years. Burt Neuborne, a New York University law professor and a former legal director for the American Civil Liberties Union, said that a commentator"s language, regardless of its severity, usually cannot be treated as an incitement of violence unless it includes direct instructions to individuals. He added, "It"s important not to allow that to happen. It would have a dramatic effect on the ability to speak vigorously" (Stelter, New York Times, 6/2).
Several newspapers on Wednesday published editorials and opinion pieces responding to the shooting death of Kansas abortion provider George Tiller, who was one of the few physicians in the country providing care for women in need of the procedure later in pregnancy. Summaries appear below.Editorials~ Boston Globe: Although officials are calling Tiller"s murder ""the act of an isolated individual," ... the generalized culture of violence and hate in the antiabortion movement that feeds the fanaticism of disturbed individuals with guns is not so easily explained away," a Globe editorial states. The editorial notes, "Many responsible abortion opponents, including Americans United for Life, condemn the killing," but "other so-called pro-life leaders insist on finding a moral equivalence between Tiller"s murder and abortion." The editorial continues, "Also victimized by Tiller"s murder are the anguished women who have sought late-term abortions because their pregnancies have gone horribly wrong." According to the editorial, the "sad irony" is that these procedures "are not a matter of "choice,"" as the "overwhelming majority of these women desperately wanted their children to be born." It adds, "Tiller"s brave and compassionate care saved the lives of these women and their futures as mothers." In his speech last month at the University of Notre Dame"s commencement ceremony, President Obama "called for people of good will on both sides of the abortion issue to bridge the divide," the editorial states, concluding, "An end to the hateful rhetoric over issues of faith that lead unhinged individuals to murder would be a good place to start" (Boston Globe, 6/2).~ USA Today: Tiller"s "insistence" on continuing to practice, despite protests and threats of violence, "was remarkably courageous," but, "[r]egrettably, threats by antiabortion activists have worked all too well," a USA Today editorial states. According to the Guttmacher Institute, the number of abortion providers has decreased by 40% since a peak in 1982, and 87% of U.S. counties have no provider, forcing many women to travel long distances to obtain care, the editorial says. "Mainstream pro-life groups should not be blamed for the actions of a suspected killer who appears to have lurked in the violent and twisted fringe of the movement," the editorial continues. However, the "braying of cable TV hosts," such as Fox News" Bill O"Reilly, "and activists such as Operation Rescue founder Randall Terry contributes to a climate of intolerance that can encourage deranged individuals," the editorial says. According to USA Today, "Thwarted in legislatures and courts, some antiabortion activists are achieving with intimidation and harassment what they can"t through the political process," but "[r]egardless of personal beliefs about abortion, authorities have an obligation to protect those providing and receiving abortion services, and to prosecute those who harass or threaten them." The editorial concludes that "Tiller"s death will only be compounded if it frightens away more doctors and makes a legal procedure even harder to come by" (USA Today, 6/3).~ Washington Post: Tiller"s death "is a tragedy for his family, his patients and his profession," and "[i]t should serve as a wake-up call that more must be done to ensure that women have access to this legal procedure," a Post editorial states. "It is unclear how this violence has affected decisions by health care providers," according to the editorial. However, it is clear that "the number of places where women can go for abortions has been declining since 1982," and "[v]ery few are performed in hospitals -- a sign that mainline medicine is not living up to its responsibility," the editorial says. The editorial notes that Attorney General Eric Holder "is offering U.S. Marshals Service protection for abortion clinics and the doctors who staff them," concluding, "It"s the right call, but one that underscores the urgency of coming up with better solutions for the delive
High profile outbreaks associated with the viruses have kept EMSL Analytical scientists busy.
Low Medicare reimbursement rates are not keeping up with costs at hospitals in Iowa and California while a grant helps boost Medicare enrollment in Missouri.
The Centers for Medicare & Medicaid Services is preparing to revive competitive bidding program for durable medical equipment that industry members helped sink last summer when it was originally scheduled to take effect, CQ HealthBeat reports. The agency had anticipated a 26 percent savings for wheelchairs, oxygen tanks and other pieces of equipment through the program. But a lobbying group for the suppliers, the American Association for Homecare, successfully urged Congress to shut down the program before it went into effect.
Researchers at the University of Tennessee Health Science Center (UTHSC) are recruiting participants for a national clinical study of medication that could slow the progression of Parkinson"s disease. The study, referred to as "QE3," will examine the effectiveness of the research medication Coenzyme Q10 (CoQ). During the study, investigators will administer high doses of CoQ to participants 30 years of age or older with early stage Parkinson"s disease to reduce the speed of their physical decline. The research is sponsored by the National Institute of Neurological Disorders and Stroke, a division of the National Institutes of Health (NIH), and will be conducted by the Parkinson Study Group, an international council of physicians and researchers experienced in caring for Parkinson"s patients and studying the disease.
The Premier healthcare alliance applauds the healthcare stakeholders group for their commitment to achieve up to $2 trillion in savings over the next decade.
In a development aimed at improving patient outcomes, physicians treating thoracic aortic aneurysms (TAA) will now experience a new level of control while placing endografts during thoracic endovascular repair procedures. With the launch of Cook Medical"s new Z-TRAK PLUS™ Introduction System, physicians are provided with improved maneuverability for controllable device orientation and deployment of the Zenith® TX2™ TAA Endovascular Stent Graft compared to earlier Cook delivery systems.
It"s a curious paradox. Black adults are more likely to smoke than white adults and most smokers start as teenagers. But statistics show that fewer black youths than whites begin smoking as adolescents.
When you were a kid your mom poured it on your scraped finger to stave off infection. When you got older you might have even used it to bleach your hair. Now there"s another possible function for this over-the-counter colorless liquid: your body might be using hydrogen peroxide as an envoy that marshals troops of healing cells to wounded tissue.
This paper investigates 26 patients with painful metal-on-metal resurfacing arthroplasties and describes three tests for the investigation of the phenomenon. The tests are metal artefact-reduction MRI, 3-D CT measurement of the position of the component and inductively-coupled plasma mass spectrometry.
Low energy fractures of the proximal humerus indicate osteoporosis and it is important to direct treatment in order to prevent further fractures. Therefore, in this study the authors collected data from 79 patients with fractures of the proximal humerus in order to determine if current guidelines on measurement of bone mineral density at the hip and lumbar spine were adequate to stratify the risk and to guide the treatment of osteoporosis.
Research published on 1st March 2009 investigates whether "simultaneous bilateral sequential total hip replacement (THR) would increase the rate of mortality and complications compared with unilateral THR", for both low and high risk patients.
MDCT angiography leads to accurate recommendations for successful treatment of patients with critical limb ischemia, sometimes allowing the patients to avoid more complicated surgery, according to a study performed at the Medical University of Vienna, Vienna, Austria.
With children having easier access to media and a wider variety of content, the possible negative influence on health issues such as sex, drugs, obesity and eating disorders is increased, and warrants monitoring usage and limiting access if necessary, according to a commentary in the June 3 issue of JAMA, a theme issue on child and adolescent health.
A new University of Illinois study of families adopting from foster care revealed significant declines in professional services and social support over the first three years of adoptive family life, even though parents indicated that they need continued assistance.
The discovery that adult skin cells can be "reprogrammed" to behave like stem cells has been a major scientific boon, providing a way to tap the potential of embryonic stem cells without the associated ethical quandaries. Now, in a study appearing online in JBC, researchers have created a line of such reprogrammed stem cells from adult pigs. As pigs are large animals with a physiology very similar to humans, this work provides a valuable model to study the therapeutic potential of this new "induced pluripotent stem cell" (iPS) technology.
Roche announced that oral and poster presentations highlighting results from the extensive multi-national ACTEMRA(R) (tocilizumab) clinical development program will be presented at the 10th Annual Congress of the European League Against Rheumatism (EULAR), which will take place June 10-13, 2009, in Copenhagen, Denmark. The studies evaluate ACTEMRA, a novel treatment targeting interleukin-6 (IL-6) receptors, in patients with moderately to severely active RA.