Nutrition
UN Launches Pilot Study In Uganda That Uses Text Messages To Promote Public Health
Several newspapers had articles on major players in health care reform. Douglas W. Elmendorf, director of the Congressional Budget Office, has "toiled for much of his career in the anonymous bowels of the nation"s economic superstructure," the Washington Post reports. But now, some lawmakers "think he holds the fate of public policy in his hands." After delivering a "skeptical analysis of a stimulus package intended to rescue the U.S. economy" and forecasting "bigger-than-expected losses from a $700 billion bailout of the U.S. financial system, Elmendorf now "faces the toughest task of his brief tenure: attaching a price to a monumental overhaul of the nation"s health-care system." Sen. Max Baucus, D-Mont., has "publicly lectured Elmendorf, saying he has a moral duty to be "creative" and deliver the favorable budget estimates "we have to have" to win broad support." But Elmendorf says "his office will offer an objective analysis, "without regard to the political consequences."" Elmendorf told the Post that his office would provide the information, but the decision is in the hands of Congress. "CBO is not going to make or break health-care reform," he says.
Legislation seeks to fix Medicare payment rates for doctors, who are routinely underpaid for services in California, while hearings in South Dakota focus on Medicare reimbursement issues in rural areas.
In a "portrayal that defied logic," George Tiller -- the Kansas abortion provider who was murdered last month -- has been depicted "on Web sites, TV and radio talk shows and in legislative hearings as the reckless "abortionist," willing to euthanize babies close to birth just so the mother could fit into a prom dress or attend a rock concert," Barbara Shelly, a member of the Kansas City Star editorial board, writes in a Star opinion piece. She asks, "Would someone in the third trimester of pregnancy travel to the heart of Kansas and pay a $6,000 fee just to fit into a size six party dress?" Shelly adds that the "overwhelming majority of the 250 to 300 women a year" that sought abortions from Tiller in the second and third trimesters had planned their pregnancies. She profiles a Missouri college professor, pregnant with twins, who traveled to Tiller"s clinic with her husband to obtain an abortion after an amniocentesis revealed that neither fetus would survive and that she faced potentially life-threatening complications if the pregnancy continued. Shelly writes that the woman and others like her went to Tiller "heartbroken and afraid, carrying fetuses with malfunctioning kidneys, missing organs and syndromes certain to cause death in the womb or soon after birth." A smaller number were survivors of rape and incest, including young girls, according to Shelly. The "prom queen who talked her way into a late-term abortion" is a "creation of Tiller"s enemies," Shelly writes, concluding that the "real people" affected by his death are the "thousands who wrote the notes that now serve as a memorial wall to a fallen physician. They are the ones who should define his memory" (Shelly, Kansas City Star, 6/9).
Have you ever wished you could be in two places at once? Perhaps you"ve had the desire to create a copy of yourself that could stand in for you at a meeting, freeing you up to work on more pressing matters. Thanks to a research project called LifeLike, that fantasy might be a little closer to reality.
Dr. Damon T. Arnold, state public health director, announced a mosquito batch collected in St. Clair County has been confirmed as the first positive West Nile virus test results in southern Illinois this year.
Dr. Mark Horton, director of the California Department of Public Health (CDPH), warned consumers not to eat SENG Chen PiMei Candy, after tests by CDPH found unacceptable levels of lead. Consumers in possession of the candy should discard it immediately.
The United Nations World Food Programme (WFP) announced the
GenWay Biotech, Inc., a US-based diagnostic company which specializes in providing protein and antibody solutions, announced its partnership with AMDL, Inc., a US-based pharmaceutical company with major operations in China, regarding the distribution of AMDL"s DR-70 (FDP) cancer test in both the United States and Canada. GenWay Biotech will be the exclusive distributor of the DR-70 test for general cancer screening by CLIA laboratories in the United States and for lung cancer screening in Canada. The commercialization efforts include raising awareness of the disease and demand creation for the test through multiple media channels and healthcare outreach. Both exclusive distribution agreements extend for five-years based on continuing success in both the Canadian and US markets.
New research published in the June issue of the Journal of the American College of Surgeons reveals that in counties with the highest levels of segregation, an increase in the African-American or Hispanic population was associated with a decrease in the availability and use of surgical services and an increase in the number of emergency room visits. This research supports prior studies that have shown that minority groups in the United States have comparatively poorer access to a range of health care services, often resulting in late diagnosis of illness and delayed treatment.
Cardiovascular disease researchers at Tulane University are partnering with faculty at the University of Buenos Aires, Argentina, to establish the South American Center of Excellence in Cardiovascular Health. The center has received a five-year, $2.3 million dollar grant from the National Heart, Lung and Blood Institute of the National Institutes of Health.
The body mass index (BMI) and waistline measurement overestimate obesity in blacks, according to a new study. The results, which were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C., suggest that conventional methods for estimating body fat may need to become race-specific.
UroToday.com - Two papers in the May 5, 2009 edition of Nature Genetics link ERG chromosomal gene translocations with loss of PTEN and the PI3-kinase pathway in the early stages of prostate cancer (CaP) progression. Both are reviewed by Urotoday.
The World Health Organization (WHO) announced it has raised the level of influenza pandemic alert from phase 5 to phase 6, following an
HCL, the UK"s largest health and social care recruiter, said today that it anticipates increasing demand for its temporary and locum staff as the NHS seeks to increase efficiencies in healthcare provision.
More than 300 infection prevention experts have completed a text that serves as one of the most valuable tools for infection preventionists throughout the world, the APIC Text of Infection Control and Epidemiology. The 1,700-page document, now in its 3rd edition, has been completely revised and is now available, offering a concise information re containing more than 120 expanded and enhanced chapters.
The benefits of alcohol are all about moderation. Low to moderate drinking - especially of red wine - appears to reduce causes of mortality, while too much drinking causes multiple organ damage.
Rogers Media is proud to join AstraZeneca Canada and Physical and Health Education Canada (PHE Canada) as a presenting partner of the school-based children"s wellness initiative, At My Best. The program addresses three key areas of wellness-physical, nutritional and emotional-and empowers teachers, parents and caregivers to inspire and motivate children and their families to make healthier choices today and develop lifelong healthy habits.
PharmaCom BioVet, Inc. (PINKSHEETS: PHMB) is pleased to announce that the Company has begun the process to potentially apply and endeavor to receive a Minor Use/Minor Species (MUMS) drug approval from the Federal Drug Administration (FDA). Meeting the MUMS requirement is part of the New Drug Approval Process if the Company decides to potentially run clinical trials on a histone deacetylase inhibitor for canines with hemangiosarcoma, which the Corporation is considering the development of. The histone deacetylase inhibitor would be directed for dogs suffering from an acute type of cancer, canine hemangiosarcoma. The Minor Use and Minor Species Animal Health Act became law in 2004.
Actelion Ltd (SIX: ATLN) announced the creation of the position of Chief Medical Officer (CMO). This change was initiated to fulfill the needs of a fast growing organization, which is developing products rapidly and managing a growing portfolio. Effective 1 July 2009, the current Head of Clinical Development, Isaac Kobrin will move into this position. He will continue to be a member of Actelion"s Executive Committee (AEC).
Insomnia is associated with increased frontal cerebral metabolism during Rapid Eye Movement (REM) sleep. Cerebral hypothermia, or cooling of the brain, has been found to reduce cerebral metabolism in other medical conditions, but its effects in insomnia are unknown.
Following today"s decision by the World Health Organization (WHO) to raise its H1N1 influenza pandemic alert to Phase 6, its highest level, Marsh, the world"s leading insurance broker and risk advisor, is recommending that all organizations continue to focus on potential economic and jurisdictional issues in shaping their response to the current pandemic.
The research group of Dr. Frç©dç©ric Charron, a researcher at the Institut de recherches cliniques de Montrç©al (IRCM), has made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. This new finding has been published in the current issue of the prestigious scientific journal Neuron. Patricia T. Yam, Sç©bastien D. Langlois and Steves Morin, all at the IRCM, are listed as co-authors.
Quintiles Consulting released the first in a three-part series of white papers addressing how best to navigate risk in drug development. The first paper, "On the Re-Balancing of Risk to Transform Cost and Productivity in Drug Development," focuses on operational risk. It is available for download at http://www.quintiles.com/consulting.
Transcept Pharmaceuticals, Inc. (Nasdaq: TSPT) announced that the U.S. Food and Drug Administration (FDA) has informed the company that it should expect to receive formal notice of a three month extension of the review period for the new drug application (NDA) for Intermezzo(R) (zolpidem tartrate sublingual tablet). The Intermezzo(R) NDA had been assigned a Prescription Drug User Fee Act (PDUFA) date of July 30, 2009. Under this revised timeline, Transcept now anticipates action from the FDA on the NDA on or before October 31, 2009.
WASHINGTON D.C. - Most patients with acromegaly who are switched to the long-acting somatostatin analogue lanreotide (SomatulineR Depot) injection from initial treatment with octreotide cite a preference for lanreotide as their future therapy, according to data released here at the 91st Annual Meeting of the Endocrine Society (ENDO 09).
Brain-computer interfaces "translate" what a person is thinking in words or actions. Researchers from Maastricht University in the Netherlands performed functional MRI brain scans on healthy participants, instructing them to "type" by performing mental tasks corresponding to different letters in the English alphabet. Researchers were able to use signals from the participants" brain activation patterns to decode information about the intended letter that a participant was thinking about, and to use this in a conversation with the experimenters without any spoken words. It is hoped that such technology can enable communication with "locked-in" patients or assessment of consciousness in non-responsive patients.
When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.
In a study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, Saint Louis University"s Center for Vaccine Development is investigating whether the standard vaccine used in foreign countries against tuberculosis offers better protection as a shot, drink or combination of both.
Older women suffering from clinical frailty stand to benefit from the first potential medical treatment for the condition, according to a study presented today by Penn Medicine researchers at ENDO, The Endocrine Society"s 91st Annual Meeting. Ghrelin, a hormone that stimulates appetite, was administered to older women diagnosed with frailty, a common geriatric syndrome characterized by unintentional weight loss, weakness, exhaustion and low levels of anabolic hormones which increases risk of falls, hospitalizations, disability, and death. Those who received ghrelin infusions consumed 51 percent more calories than the placebo group, with an increase in carbohydrate and protein intake, not fat. Their growth hormone levels were also higher throughout the ghrelin infusion.
A unique Network studying the health and wellbeing of older people is bringing together health, social science and mathematics experts in a revolutionary project which will help shape the long-term provision of health and social care services across the UK and ultimately benefit older people.
A new PTB measuring system offers the possibility of measuring the absorbed dose in the direct environment of the irradiated tumour
Researchers have been seeking a safe and effective way to treat cognitive impairments associated with schizophrenia by enhancing N-methyl-D-aspartate (NMDA) glutamate receptors. Functional deficits in NMDA receptors may contribute to the underlying neurobiology of this disorder. The first generation of studies trying to stimulate NMDA receptors administered large amounts of substances, like glycine or D-serine, which indirectly enhance NMDA receptor function. While there were some positive reports of efficacy, findings across studies were more inconsistent than was hoped.
The Soil Association is pleased to announce a new EU-wide, harmonised standard for organic health and beauty products.
Spread and extent of the outbreak (information as at 5pm on 11 June)
Merck & Co., Inc. issued the following statement in response to today"s communication from the U.S. Food & Drug Administration (FDA) addressing updated information on leukotriene inhibitors, including SINGULAIR® (montelukast sodium).
When President Obama chose Green Bay, Wis., to talk about the need for health reform, he did so in part because the area has achieved a high level of quality, and compared with other parts of the country, succeeded in restraining health care costs, National Public Radio reports. "They"re certainly spending a lot less money, and they are providing care that is equal or better than the care that is provided in many other communities around the country," Elliot Fisher, a researcher at the Dartmouth Institute for Health Policy and Clinical Practice told NPR in an interview. NPR says: "Some of the research the administration is relying on comes from the Dartmouth Institute for Health Policy and Clinical Practice," which focuses on variations in health quality and costs around the country.
A large, well-controlled, multi-national clinical trial program has demonstrated the effectiveness and safety of what may become the first FDA-approved medicine for idiopathic pulmonary fibrosis, or IPF.
Global Post examines the quest for an effective vaccine to fight malaria. According to Global Post, "epidemiologists are pinning their hopes on a malaria vaccine" because "[k]illing mosquitoes, or avoiding bites, is an imprecise solution to malaria."
The NFU has told a European Commission review of anti-dumping duties imposed on fertiliser from the Ukraine that such measures act as artificial trade barriers and, given the importance of fertiliser to agriculture, can curb profitability of farms across the UK and EU.
Men are almost 40 per cent more likely than women to die from cancer, reveals a report published today (Monday) by the National Cancer Intelligence Network (NCIN) and Cancer Research UK together with the Men"s Health Forum to mark Men"s Health Week.
Senate Minority Whip Jon Kyl (R-Ariz.), a member of the Senate Judiciary Committee, on Thursday said that the GOP has not ruled out the use of procedural tactics, such as a Republican boycott, to attempt to delay Supreme Court nominee Sonia Sotomayor"s confirmation hearing, Roll Call reports. Republicans have complained that the scheduled July 13 start date for the hearing does not give them enough time to review Sotomayor"s record. Kyl said that Republicans will try to negotiate with Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) for more time if they feel they cannot meet the July 13 deadline (Stanton, Roll Call, 6/11). Leahy said that Sotomayor is entitled to be confirmed on the same timetable as Chief Justice John Roberts, who appeared before the Judiciary Committee less than two months after his nomination (Kivlan, CongressDaily, 6/11).Republican Senate aides say Judiciary Committee ranking member Jeff Sessions (R-Ala.) is not likely to make a final decision for several weeks on whether the GOP will try to delay the nomination. According to Roll Call, Sessions has sought to approach the issue "in a careful, measured way," though he has been critical of some of Sotomayor"s public statements. Roll Call reports that Republicans are apt to display an impartial stance on Sotomayor until the hearing starts, meaning that they likely will delay a decision on whether to stall the nomination until the last minute (Roll Call, 6/11).Sen. Dianne Feinstein (D-Calif.) said that Republican senators are stalling to give conservative groups more time to organize a campaign against Sotomayor that they hope will taint her nomination. Feinstein said that there are "groups out there who need more time for attacks and sound bites." She added, "This is a woman who is qualified, who is brilliant, and who worked her way up" (CongressDaily, 6/11).
The following summarizes news coverage on women"s health-related legislation in Arizona and North Carolina. ~ Arizona: The Arizona Senate Public Safety and Human Services Committee on Wednesday voted 4-3 to approve a bill (S.B. 1206) that would place several restrictions on abortion rights and allow pharmacists or other health care providers to refuse to distribute emergency contraception based on religious or moral objections, the AP/Arizona Daily Star reports. The state House passed an identical bill in March. The measure would impose a 24-hour waiting period for women seeking abortion procedures and mandate that doctors inform women about risks and alternatives. It also would toughen an exisiting parental consent requirement for minors seeking abortion. The bill requires an in-person consultation before the 24-hour waiting period, which would increase costs for women who are forced to travel to a clinic twice, according to Planned Parenthood of Arizona President Bryan Howard. The Legislature approved bills with similar restrictions in recent years, but the measures were vetoed by then-Gov. Janet Napolitano (D). Current Gov. Jan Brewer (R) has said she supports mandatory disclosures and a 24-hour waiting period (Billeaud, AP/Arizona Daily Star, 6/10).~ North Carolina: The North Carolina Senate Mental Health and Youth Services Committee this week approved a bill (S. 221) that would require all public school systems to offer information on the use of contraceptives to students in grades seven through nine, the AP/Raleigh News & Observer reports. The information would be presented as part of a larger reproductive health education program that would maintain the abstinence-only education curricula currently taught at nearly all of the state"s 115 school districts. Parents would be permitted to prevent children from participating in the classes with contraceptive information. The measure is a revised version of state House-approved legislation (H.B. 88) that would have required schools to teach two separate abstinence-only and comprehensive sex education tracks. If the full state Senate passes the new bill, the two chambers will meet to negotiate a compromise (Robertson, AP/Raleigh News & Observer, 6/11).
Two newspapers recently published an editorial and an opinion piece in reaction to the announcement that murdered Kansas abortion provider George Tiller"s Wichita clinic would be permanently closed. The clinic was one of a handful in the U.S. offering abortion procedures in the second and third trimesters. Summaries appear below.~ Kansas City Star: The closing of Tiller"s clinic is "a tragedy for American democracy," and the "irrational violence" of his death has "trumped public policy," a Star editorial states. "The basis of civilization is that we agree to submit to the rule of law in order for society to flourish," the editorial says, adding that Tiller"s murder is "antithetical to that principle. It is dismaying to see a killer achieve his objective." The editorial notes that Tiller provided abortion services in "tragic cases" involving women "at risk of infertility or death; fetuses with severe abnormalities; and victims of rape and incest." It continues that the "reduction or loss of that service will create hardships and may put women"s lives at risk." Hospitals and doctors who refer such cases to abortion providers "must reassess the circumstances under which they would perform late-term abortions," according to the editorial. In addition, the "medical profession must take a role in training and supporting doctors willing to provide abortions," and the government and local police "must do all they can to protect a legal medical practice," the editorial says. It concludes, "Democracy demands that we not allow murder to make de facto public policy" (Kansas City Star, 6/11).~ Eric Zorn, Chicago Tribune: The announcement that Tiller"s clinic will remain permanently closed "was simply more proof that violence and intimidation can get results where civil discourse and political process fail," Tribune columnist Zorn writes. "The question isn"t whether prominent foes of abortion rights are being honest with us when they decry Tiller"s violent death and express regret over the means used to achieve an end they"ve sought," Zorn writes, adding, "Some are, I"m sure." He continues that abortion-rights opponents "recognize that ... a movement calling itself "pro-life"can"t also be pro-murder" and "are politically savvy enough to know that the gains won by terrorist acts are grudging and difficult to sustain." He continues that to "make terrorism less effective, and thereby discourage it," abortion-rights advocates, the medical profession, politicians and law enforcement officials "need to reopen that clinic in Wichita and assure its safe operation ... to defy terrorism, if for no other reason." He concludes that "as long as abortion remains legal, this same coalition needs to strive to expand the number of facilities where it"s available" (Zorn, Chicago Tribune, 6/11).
The U.S. Food and Drug Administration provided further updated safety information on a class of asthma drugs known as leukotriene modifiers. The FDA has requested that manufacturers include a precaution in the drug prescribing information (drug labeling) regarding neuropsychiatric events (behavior, mood changes) that have been reported in some persons taking montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo and Zyflo CR).
A novel bacterium that has been trapped more than three kilometres under glacial ice in Greenland for over 120 000 years, may hold clues as to what life forms might exist on other planets.
Human Genome Sciences (HGS) has reported continuation data from a Phase II study of BENLYSTA™ (belimumab, formerly LymphoStat-B®) showing sustained improvement in patients with active systemic lupus after four years of treatment. The data was presented at the EULAR 2009 scientific meeting in Copenhagen, Denmark.
Honoured guests, ladies and gentlemen, welcome to the annual BVA Scottish dinner and a particularly warm welcome to our host this evening, John Scott MSP - we are incredibly grateful for your continued support to the BVA - and to the Environment Minister Roseanna Cunningham for kindly agreeing to address us this evening.
Individuals suffering from chronic obstructive pulmonary disorder (COPD) can experience significant savings in healthcare costs by employing a self-treatment program with the judicious use of medications, according to the results of a new study. The self-treatment program achieves these savings by reducing the duration of flare-ups.
New wireless keyboards for use with hospital patient entertainment and point-of-care terminals are hygienic, monitoring their own disinfect status to give reminders when sterilisation is due.
The Health and Safety Executive (HSE) is reminding employers of their duties to the safety of staff following an incident in Kettering where an employee fell six foot and suffered serious injury.
Yissum Research Development Company Ltd., the Technology Transfer Company of the Hebrew University of Jerusalem, announced today at the ILSI-Biomed Israel 2009 conference, it has signed an agreement with Aurum, Ventures MKI, the technology investment arm of Mr. Morris Kahn, for the development of a nanotechnology controlled release drug delivery platform that increases the bioavailability of orally administered lipophilic drugs. The technology was developed by Prof. Simon Benita at the Hebrew University"s School of Pharmacy.
Gallstones are lumps or stones that develop in the gallbladder or bile duct. Some of the chemicals which exist in the gallbladder, such as cholesterol, calcium bilirubinate, and calcium carbonate, harden into either one large stone or many small ones. According to Medilexicon"s medical dictionary, a gallstone is "A concretion in the gallbladder or a bile duct, composed chiefly of a mixture of cholesterol, calcium bilirubinate, and calcium carbonate, occasionally as a pure stone composed of just one of these substances". An article describes a gallbladder in the bile duct similar to trying to squeeze a golf ball through a straw.
Drinking a glass of skimmed milk, rather than fruit juice, at breakfast time could leave you feeling fuller for longer and less likely to eat heavily at lunchtime, according to new research.
BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, announced it is filing an application with the U.S. Food and Drug Administration (FDA) for 510(k) clearance to market its Allay™ Menstrual Pain Relief Patch product. The filing follows a very successful double blinded, placebo controlled clinical trial in which 71% of women in the active group reported either complete elimination or a reduction in their typical menstrual pain symptoms, with 49% showing at least a 50% reduction in pain associated with dysmenorrhea.
Boston Scientific Corporation (NYSE: BSX) announced that results from nine studies involving the Company"s Urology/Gynecology products will be presented at the 34th Annual Meeting of the International Urogynecological Association (IUGA). Presentations will feature Boston Scientific"s pelvic floor reconstruction systems and mid-urethral sling systems used to treat pelvic floor prolapse and stress urinary incontinence (SUI). The Company will also sponsor a symposium highlighting long-term registry data comparing the benefits of experienced-based versus evidence-based outcomes for patients treated with mid-urethral slings. The IUGA Congress will be held June 16-20 at the Villa Erba Conference Center in Como, Italy.
Protein Sciences Corporation (PSC) announced that it commenced manufacturing of a vaccine to protect humans against the H1N1 "swine flu" virus. The Company estimates that it can produce 100,000 doses this week and at least 100,000 doses per week thereafter. The vaccine, called PanBlok(R), is made using PSC"s proprietary baculovirus and insect cell manufacturing technology. PSC believes that PanBlok is the first and only vaccine that could be used to protect against the escalating worldwide pandemic, at least for the next few months.
Geisinger Health System senior investigator and U.S. Army veteran Joseph Boscarino, Ph.D., is proud of his military service, yet he doesn"t like to talk much about his combat experiences.
Sanofi Pasteur, the vaccines division of sanofi-aventis Group (EURONEXT: SAN and NYSE: SNY), announces it is ready to support public health efforts to respond to the emergence of the new A(H1N1) influenza strain following the decision made by the World Health Organization (WHO) to raise the pandemic alert level from Phase 5 to Phase 6, the highest level of alert in the WHO global influenza preparedness plan.
Wrong Way On Health Reform Washington Post
Nigel Ellis, Head of National Assessment and Inspection at the Care Quality Commission said, "The NAO is right to acknowledge improvements in the control of MRSA and C. difficile, which have had such a strong grip on hospitals in this country. This follows a big effort from people right across the NHS - and we are of course pleased that the report recognises the role that independent regulation has played.
You"ve just won a prize. Would you like to find out what it is right away, or wait until later? A new study in the Journal of Consumer Research says most people are happier waiting.
Today, the Israeli medtech startup company CLT Ltd. announced the establishment of Closed Loop Therapies (CLT) BV - a joint venture between Erasmus University Medical Centre (Rotterdam, the Netherlands), a highly prominent medical institute in Europe, and CLT Israel. The joint venture aims to develop and commercialise a novel therapeutic system, consisting of an arrhythmia-detecting drug pump combined with a unique drug, for automatic and immediate treatment of emerging atrial fibrillation (AF). Market size is estimated at 2.5-3 billion Euro, annually.
In response to the House of Commons Public Accounts Committee End of Life Care Report published Ruairi O"Connor, Head of Policy and Public Affairs at the British Heart Foundation (BHF) said:
Celgene Corporation (NASDAQ: CELG) announced the preliminary results of a phase II, multi-center, randomized, double-blind, placebo-controlled, three-arm study of apremilast - a novel, orally available small molecule that exhibits anti- inflammatory activities through the suppression of multiple pro-inflammatory mediators and cytokines - in adult patients with psoriatic arthritis (CC-10004-PSA-001). The study met its primary objective of assessment of ACR20 at 12 weeks. ACR20 is defined as the percentage of patients achieving a 20% or better improvement according to the American College of Rheumatology (ACR) criteria. ACR20 is the primary assessment utilized by the U.S. Food and Drug Administration for assessment of efficacy in psoriatic arthritis, as well as rheumatoid arthritis.
Alcohol-related deaths among U.S. college students rose from 1,440 deaths in 1998 to 1,825 in 2005, along with increases in heavy drinking and drunk driving, according to an article in the July supplement of the Journal of Studies on Alcohol and Drugs.
One of the mechanisms governing how our physical features and behavioural traits have evolved over centuries has been discovered by researchers at the University of Leeds.
New York: With a growing recognition that "blind faith in economic growth and gain as the be-all, end-all, cure-for-all has been misplaced," World Health Organization Director-General Dr Margaret Chan responded to leaders who have been calling for a redesign of international systems.
Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology. A mutant protein makes the microtubules too stable to perform their jobs, the researchers find.
Recently, researchers at the European Molecular Biology Laboratory"s European Bioinformatics Institute (EMBL-EBI) launched a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.
Responding to the World Health Organisation"s recent confirmation of swine flu as a pandemic, BMJ Learning, the medical education arm of the BMJ Group, has updated and revised its guide "Influenza pandemics: why, what, and how to prepare" which covers all the information doctors need to know about pandemic flu including details of the epidemiological features and a description of the viruses involved.
Rush University Medical Center is the only hospital in Illinois and the only hospital in the Midwest to receive the highest possible rating in the Healthcare Equality Index 2009 (HEI), which is an annual survey that evaluates the nation"s hospitals on their treatment of lesbian, gay, bisexual, and transgender (LGBT) patients, their families and hospital employees.
The European Medicines Agency has been formally notified by Sepracor Pharmaceuticals Ltd of its decision to withdraw its application for a centralised marketing authorisation for the medicine Lunivia (eszopiclone), 2 and 3 mg tablets.
Henry Ford Health System, one of the nation"s top rated health systems and recognized visionaries in offering quality care, formally announced its adoption of Healthy Interactions U.S. Diabetes Conversation Map® education program in its diabetes education curriculum, proclaiming them to demonstrate increased effectiveness in helping patients with diabetes live with their condition. The five Conversation Map tools, which were developed in collaboration with the American Diabetes Association and sponsored by Merck & Co., are based around large colorful 5 ft by 3 ft discussion displays.
Breast cancer researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a prestigious Department of Defense Synergistic Idea Award, one of just 12 such grants in the United States. The $725,000 research grant over two years will allow Lisa Baumbach, Ph.D., associate professor of pediatrics at the Miller School, and Mark Pegram, M.D., professor of medicine and associate director for clinical and translational research at the Braman Family Breast Cancer Institute at Sylvester, to expand their work examining the genetic differences found in African-American breast cancer patients.
Abbott (NYSE: ABT) announced the initiation of SPIRIT PRIME, a clinical trial to study the performance of the company"s next-generation XIENCE PRIME(TM) Everolimus Eluting Coronary Stent System, currently an investigational device, for the treatment of coronary artery disease. Results from SPIRIT PRIME will be used to support the regulatory filing for XIENCE PRIME in the United States. The first patient was enrolled into the SPIRIT PRIME clinical trial at Hillcrest Medical Center in Tulsa, Okla., by Rajesh Chandwaney, M.D.
Scientists at the University of California, San Diego School of Medicine have shown that a fully automated procedure called Volumetric MRI which measures the "memory centers" of the brain and compares them to expected size is effective in predicting the progression from mild cognitive impairment (MCI) to Alzheimer"s disease. The procedure can be readily used in clinics to measure brain atrophy, and may help physicians to predict decline in MCI patients. Their study has been published in the June issue of the journal Alzheimer Disease and Associated Disorders.
In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging. They found that as cells and tissues age, the expression of a key protein, called p16INK4a, dramatically increases in most mammalian organs. Because p16INK4a is a tumor suppressor protein, cancer researchers are interested in its role in cellular aging and cancer prevention.
Nanoparticles specially engineered by
Some things in life are multi-purpose. Now miniature technology used to cool the central processing units in computers may have found a use in mainstream medicine!
Over 158 million people in the world are effectively blind because they do not have the spectacles they need to correct their vision. The cost of this disability is enormous. A recent study published in the Bull World Health Organ claims that uncorrected refractive error results in a loss of economic productivity globally worth $427 billion.
NPR reports on the health care struggles of Howard County, Maryland, a well-off and generally liberal area with hospital fees set by the state and a county program for the uninsured. "But like the rest the country, Howard County is facing the impact of the recession: Employers have to cut back on benefits, so employees cut back on their coverage." Herb Huston, 61, lost his employer-provided insurance when he was laid off a few years ago. He"d always been healthy, but one night in May he suffered a heart attack. "Neither old enough for Medicare nor poor enough for Medicaid," Huston will be responsible for the costs himself, which "should easily exceed $50,000." On the other end of the spectrum is 62-year-old Judy Weeter, who pays no premium for the insurance she receives through her employer. She"s undergoing expensive chemotherapy for breast cancer but expects to pay no more than her $20 copays.
The following summarizes selected women"s health-related blog entries. ~ "Report: Higher Rates of Unintended Pregnancy, Abortion Among Women of Color," Sharon Camp, RH Reality Check: A new report from the Kaiser Family Foundation on health disparities between white women and women of color "provides further stronger evidence debunking claims" from antiabortion-rights advocates who "have long argued that high abortion rates among minorities are the result of supposed aggressive marketing by abortion providers to minority communities," Camp, president and CEO of the Guttmacher Institute, writes. In addition to identifying disparities in conditions like heart disease and cancer, the report documents "widespread disparities in access to health insurance and health screenings" and explores growing evidence of the association between social factors and health behaviors, access and outcomes, according to Camp. She continues that research from Guttmacher has consistently demonstrated that "rates among racial and ethnic minorities -- especially blacks and Hispanics -- are directly linked to their higher rates of unintended pregnancy, which in turn reflect pervasive health disparities more generally." Camp writes that the "fundamental question policymakers should be asking is not why women of color have high abortion rates, but rather what can be done to help them have fewer unintended pregnancies and achieve better health outcomes more generally," such as improved access to affordable contraception. Women"s dissatisfaction with health care providers, quality of service and the contraceptive methods themselves also are factors in contraceptive use, as are "[u]nstable life situations," which can make consistent use a low priority for some women, according to Camp. She writes, "By continuing to label abortion providers as "racists" and refusing to support expanded access to contraceptive services, antiabortion-rights activists are by no means part of the solution -- to high rates of unintended pregnancy and abortion among racial and ethnic minorities or to persistent and tragic disparities in health care generally" (Camp, RH Reality Check, 6/15).~ "What"s Next for Women"s Legal Rights in the Supreme Court?" Amy Matsui, Womenstake: Matsui, senior counsel for the National Women"s Law Center, examines several women"s rights issues "that we see peeking around the corner" of the next Supreme Court session. Matsui writes that "increasingly draconian abortion restrictions have begun to work their way through state legislatures." These restrictions include giving personhood rights to fetuses, mandates on the information women are given prior to abortion procedures and "outright abortion bans," she writes. Challenges to laws that expand protections for providers who deny health care services also "are likely to come before the courts," Matsui writes. Challenges to health care reform proposals also are likely, "specifically, the interaction of the federal statute that governs employee health care and pension plans ... and any new requirements for employers to provide health care coverage," according to Matsui. The Supreme Court has "obviously considered the underlying legal doctrines in these cases (the constitutional right to privacy, federal anti-discrimination statutes, Equal Protection guarantees and federal benefits statutes) in the past; some might say that there is a clear roadmap of where the Court should go in some of these cases," Matsui writes, concluding, "But when every vote counts on the Supreme Court, women should be watching what cases come next" (Matsui, Womenstake, 6/12).~ "Antiabortion Groups" Case Against Sotomayor," Dan Gilgoff, U.S. News & World Report"s "God and Country": "With no clear evidence for a pro-abortion-rights position in her judicial decisions, antiabortion groups" case against Supreme Court nominee Sonia Sotomayor can be summed up in eight words: the Puerto Rican Legal Defense and Education Fund," Gilgoff writes. From 1980 to 1992, Sotomayor sat on the l
The American Society of Health-System Pharmacists (ASHP) has named Fela Viso-Gurovich, Ph.D., an honorary member of the Society for her pioneering work in the development of hospital pharmacy in Mexico. Dr. Viso-Gurovich received the honor during ASHP"s Summer Meeting in Rosemont, Ill.
Taking popular cholesterol-lowering statin drugs, such as Lipitor® (atorvastatin), does not lower the risk of pneumonia. That"s the new finding from a study of more than 3,000 Group Health patients published online on June 16 in advance of the British Medical Journal"s June 20 print issue.
Utopia Home Care, Inc. has announced that Michelle Harris will be its 2009 Caregiver of the Year. At the company"s annual corporate breakfast meeting this morning, Utopia Home Care, Inc. President and CEO Manuel F. Martinez and Executive Vice President Manuel G. Martinez presented Ms. Harris with a commemorative plaque and a check for $1,000. The presentation was made before approximately 125 staff members representing Utopia offices in New York, Connecticut, Florida, South Carolina and Pennsylvania.
More than half of the UK population feels that a breakdown in communications between healthcare agencies would allow a pandemic outbreak such as swine flu to spread unnecessarily and slow the effective distribution of vaccines, according to a survey by specialist healthcare technology consultants, 21C.
The kids are playing in the backyard and enjoying their break from school. Your husband is enjoying the day on the golf course. And you"re cleaning up the house, folding laundry and cooking three meals. Sound familiar?
With one in five, or 60 million, Americans suffering from some kind of allergy, spring and summer can be a difficult time of year as pollen, moisture and humidity increase. According to the Asthma and Allergy Foundation of America, allergies are considered the fifth leading chronic disease and are a major cause of work absenteeism, resulting in nearly four million missed or lost workdays each year.
Measures contained in the budget will help attract and retain more doctors to rural and remote areas, the AMA said today.
To determine if guided fat (adipose) precursor cells (APCs) could improve nerve regeneration and functional recovery, researchers at the University of Pittsburgh (USA) used biodegradable nerve guides to transplant APCs into the injured peripheral nerves of laboratory rats.
University of Louisville neurologist Robert P. Friedland, M.D., questions the safety of eating farmed fish in the June issue of the Journal of Alzheimer"s Disease, adding a new worry to concerns about the nation"s food supply.
A coalition of organizations representing healthcare stakeholders throughout Greater Boston has been selected by the Robert Wood Johnson Foundation (RWJF) to participate in a planning grant to become part of the Aligning Forces for Quality (AF4Q) initiative. AF4Q is the Foundation"s signature effort to lift the overall quality of healthcare in targeted communities, reduce racial and ethnic disparities, and provide models for national reform.
The Association for Molecular Pathology (AMP) recently released the text of a comment letter it has provided to the Federal Coordinating Council for Comparative Effectiveness Research (CER) in which AMP sets forth its recommendations for priority areas on which to focus CER activities.
Contur Software, a leading provider of electronic laboratory notebook (ELN) systems, announced added chemistry functionality in iLabber, the company"s recently launched high-end ELN system available as an online service. Using a software as a service (SaaS) model, Contur Software is making iLabber available to individual researchers and smaller R&D organizations that previously have not been able to utilize the advantages of high-end ELN systems due to investments in hardware, licenses and maintenance.
Our brains get a first impression of people"s overriding social signals after seeing their faces for only 100 milliseconds (0.1 seconds). Whether this impression is correct, however, is another question. Now an international group of experts has carried out an in-depth study into how we process emotional expressions, looking at the pattern of cerebral asymmetry in the perception of positive and negative facial signals.
Researchers working with Dr Marcus Schmidt in the Department of Obstetrics and Gynecology at the University Medical Center Mainz have unlocked the key to the immune system"s significance in cases of breast cancer, thus identifying its long-neglected role in the prognosis of the disease. Their research results, published in the renowned Cancer Research journal, show that patients with certain breast tumors have a better prognosis when more immune cells are present in the tumor. These results permitted the scientists to extend the "coordinate system" in case of breast tumors to include the immune system as the third important reference point for the prognosis of this disease, in addition to the long-established prognostic factors of estrogen receptor expression and proliferative activity (Cancer Research, 1 July 2008; Cancer Research, 1 April 2009).
A new theory on the role of developmental experiences is presented in the current issue of Psychotherapy and Psycosomatics.
Ladyhawke will play an exclusive gig for just one personò€¦ and their online social network. The new "Skindividual" initiative, from SunSmart (Cancer Research UK"s skin cancer awareness campaign), aims to encourage young people to protect their skin from too much UV by harnessing the power of social networks and rewarding those who grow the biggest online guestlist.
Humans can tell if two strangers are related, even if they are generations apart, just by looking at their faces. So say scientists writing today in the journal Proceedings of the Royal Society B , who believe this ability helps us to interpret situations and understand the motives of others in a social setting.
BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, announced its sponsorship of a groundbreaking clinical study on musculoskeletal disorders. The randomized, double blinded and placebo-controlled study will be supervised by a primary investigator, Sheena Kong, MD of San Francisco, California in conjunction with several other leading physicians.
Parents of babies and young children are being urged to stop using the "First Steps" medicine feeder range manufactured by RSW International Ltd after the Medicines and Healthcare products Regulatory Agency (MHRA) uncovered potential safety and quality concerns.
"Democrats Tom Daschle and George Mitchell are set to join Republicans Bob Dole and Howard Baker on Wednesday to release a $1.2 trillion proposal that would be fully paid for with a combination of spending cuts and tax increases," the Associated Press reports. The proposal from the four former Senate leaders "combines ideas from both political parties to guarantee coverage for all" and is an attempt to "prevent a repeat of the 1990s standoff over health care."
Los Angeles County public health officials on Tuesday said that they cannot confirm that the 16 cases of HIV they reported last week were in fact active adult film industry workers at the time of their diagnoses, the Los Angeles Times reports. Officials contend that they mistakenly labeled all cases of individuals who tested positive from the Adult Industry Medical Foundation (AIMF) clinic since 2004 as "adult performers," even though AIMF also serves clients who are not in the industry. In addition, officials increased the total number of cases of HIV reported by the clinic since 2004 from 16 to 18 (Yoshino/Lin, Los Angeles Times, 6/17).
ECRI Institute Patient Safety Organization (PSO) is pleased to announce an agreement with the Coalition for Quality & Patient Safety (CQPS) of Chicagoland PSO to provide patient safety data collection, reporting, and analysis. The Chicagoland PSO focuses on local experience, patterns, trends, and patient safety initiatives specific to Chicago and the surrounding counties. CQPS will coordinate its PSO and other patient safety efforts with other Illinois-based hospital and primary care associations, the Illinois Department of Public Health, consumers and consumer advocates, other patient safety and quality improvement stakeholders, and existing patient safety collaboratives across the state.
Tennessean columnist Getahn Ward examined the "Cure CVS: Unlock the Condoms Initiative," led by the group Change to Win, which claims that the pharmacy chain"s practice of locking up some condoms in certain neighborhoods might decrease access for young adults and minorities, potentially increasing their risk of HIV and unintended pregnancy. CVS contends that the practice is used as a theft deterrent but said it does have some condoms available that are not locked up. Officials from Walgreens say their stores do not lock up condoms, and Rite Aid officials say they do not have a specific policy in place, but access to some personal items, including condoms, does require the assistance of an associate at stores with much theft (Ward, Tennessean, 6/17).
Today, The Endocrine Society announced Newsweek Reporters Barbara Kantrowitz and Patrice Wingert recipients of the Society"s second annual Award for Excellence in Science and Medical Journalism. The co-authors of the winning article, "Uh, O!" (O for Oprah) were honored last night at the Society"s 91st Annual Meeting in Washington, DC.
CMOS image sensor (CIS) technology stands on the brink of fulfilling its potential to become the global detector platform of choice for scientific photonics applications that require world class performance in the fields of sensitivity, speed, dynamic range, resolution, and field of view.
In response to the recent Food and Drug Administration action, Evanger"s Dog and Cat Food Co., Inc. has filed a formal request, as allowed by FDA regulations, for reinstatement based on documentation that the company is operating in full compliance with mandatory requirements.
Insecticides used in and around homes - including products voluntarily removed from the market years ago - were measured on the floors of U.S. residences, according to the first study large enough to generate national data on pesticide residues in homes. It is scheduled for the June 15 issue of ACS" semi-monthly journal Environmental Science & Technology.
VaxInnate Corporation today reported positive preclinical results for a recombinant swine flu vaccine it developed in less than three weeks, making it one of the first companies in the world to begin testing a vaccine that could help halt the spread of the swine flu pandemic.
Our ability to withstand stress-related, inflammatory diseases may be associated, not just with our race and sex, but with our personality as well, according to a study published in the July issue of the journal Brain, Behavior and Immunity. Especially in aging women, low levels of the personality trait extraversion may signal that blood levels of a key inflammatory molecule have crossed over a threshold linked to a doubling of risk of death within five years.
Diagnostic display monitors have experienced slow growth in 2007 due to picture archiving and communication system (PACS) installations across radiology departments of European hospitals having reached saturation. However, favourable regulations mandating the sales of 5MP displays for digital mammography have ensured high-volume sales in several European countries. The increasing demand for clinical review display monitors from private practitioners has also ensured very high growth rates for medical imaging display monitors.
Antisense Therapeutics Ltd. (ASX: ANP) is pleased to report further positive results from its collaborative preclinical research studies on the therapeutic potential of ATL1101 in prostate cancer. In experimental models, ATL1101 treatment significantly enhanced the tumor-suppressive effect of the cancer drug Paclitaxel. Paclitaxel is one of a class of drugs known as taxanes. Along with androgen (a male hormone) blockade, taxane chemotherapy is an important treatment option in the most dangerous form of the disease, castration-resistant prostate cancer (CRPC).