Cardiovascular
In a disappointing move, the Food and Drug Administration (FDA) did an about face in issuing a final regulation classifying dental amalgam without calling for stringent precautions for pregnant women and children. Last June, a court settlement filed by the Consumers for Dental Choice required the FDA to withdraw claims of mercury amalgam"s safety from its Web site and issue an advisory indicating: "Dental amalgams contain mercury, which may have neurotoxic effects on the nervous systems of developing children and fetuses."
The unique association between microorganisms and their hosts, whether insects, plants, or mammals, provides a fascinating view into how microbial symbionts adapt to changing biological environments. Insights into the diversity and complexity of symbiotic relationships are the focus of the current special issue of DNA and Cell Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. The issue is available free online at http://www.liebertpub.com/dna
DLX5, a gene crucial for embryonic development, promotes cancer by activating the expression of the known oncogene, MYC, according to researchers from Fox Chase Cancer Center. Since the DLX5 gene is inactive in normal adults, it may be an ideal target for future anti-cancer drugs, they reason. Their findings are published in the July 31 edition of the Journal of Biological Chemistry, available online now.
Nearly three decades after China implemented its one-child policy, the city of Shanghai is planning to encourage young couples to have a second child in an effort to address the country"s aging population and shrinking work force, the New York Times reports. The city"s plan is the most public effort made by the government to counteract a program that is "considered both a tremendous success and a terrible failure," the Times reports. The policy has managed to keep population growth under control but also has led to forced abortions, according to the Times.The country is not abandoning the one-child policy, which applies mostly to residents in urban areas. Rather, the government is allowing more exceptions to the rule, with Shanghai -- where about 22% of its 20 million residents are older than age 60 -- leading the effort. China as a whole faces a similar problem seen in Shanghai, the Times reports. About 8% of the country"s population was older than age 65 in 2006. That figure is expected to increase threefold by 2050 to about 322 million people, or nearly 25% of the population, according to the United Nations.In Friday"s issue of China Daily, Xie Lingli, director of the Shanghai Population and Family Planning Commission, was quoted as saying, "We advocate eligible couples to have two kids because it can help reduce the proportion of the aging people and alleviate a work force shortage in the future." City officials plan to visit homes, pass out leaflets, and offer counseling and financial incentives, the Times reports. Current exceptions to the one-child policy are in place for ethnic minorities and rural residents, who can have a second child if the first child is a girl. Couples made up of two parents who have no siblings have always been allowed to have a second child and are now being encouraged to do so (Barboza, New York Times, 7/24).
The following summarizes selected women"s health-related blog entries. ~ "Mainstream Media Reinforces Unexamined Arguments Against Public Funding for Abortion," Amanda Marcotte, RH Reality Check: It "seems that mainstream media s ... believe that abortion is an effective cudgel to beat health care reform to death," Marcotte writes. According to Marcotte, the "unvarnished truth" is that there is "no way that any kind of public health care plan will have elective abortion coverage. Nor is there any real chance of abortion becoming mandated coverage." However, "you wouldn"t know it to read the media coverage of this issue," she writes, continuing that "we"ve got the toxic mixture of pants-on-fire lying anti-choicers and cowardly media outlets that give the opponents of health care reform an opportunity to lie about the potential for taxpayer-funded abortions." Those who defend health care reform are "so busy trying to shut down the misinformation about abortion coverage that we"re not having the more interesting discussion about whether or not abortion should be covered," Marcotte says. She adds, "And by not having that discussion, we"re allowing the belief that some people"s moral objections to abortion should dictate federal policy lay unchallenged," she continues. She writes that she "suspect[s] that anti-choicers latched onto taxpayer-funded abortions because they can count on a lot of the public to imagine the government funding female licentiousness." Marcotte concludes that the "good news is that this contempt for female sexuality has receded enough that the media debate hasn"t -- yet -- turned to whether or not health care reform should cover contraception" (Marcotte, RH Reality Check, 7/28).~ "Privileging Opposition to Abortion," Jamison Foser, Media Matters for America: Some reporters "have skewed their reports in favor of those who oppose" coverage of abortion in federally subsidized insurance plans, according to Foser. For example, Foser writes that on a recent episode of MSNBC"s "Hardball," host Chris Matthews asked Sens. Richard Durbin (D-Ill.) and Orrin Hatch (R-Utah) "leading questions that encouraged them to state their opposition to insurance coverage of abortion" but never asked them "one simple question: Why shouldn"t abortion be covered, given that the procedure is legal?" Foser adds, "Nor has he asked if there are any other legal procedures that shouldn"t be covered." The "premise that taxpayers who oppose abortion shouldn"t have to pay for them with their tax money carries obvious implications the media ignores," Foser writes. He adds that the "idea that taxpayers shouldn"t pay for insurance that covers medical services they don"t support is fundamentally incompatible with the very concept of insurance." He continues, "If every interest group wields veto power over the medical care insurance can cover, insurance simply can"t work." However, this is not the "only logical inconsistency on the part of abortion foes that the media fail to examine" in their coverage of abortion issues in the health reform debate, he writes. "Many of those who are most adamant that the government not allow abortion to be paid for by health insurance plans are the same conservatives who argue against health care reform by warning of the prospect of a government bureaucrat getting between you and your doctor," according to Foser. He continues that the "same people who want a government ban on insurance coverage for a legal medical procedure turn around and demagogue about government bureaucrats making medical decisions," which is "a pretty obvious inconsistency, the kind any reporter should be able to spot easily." However, the "tension between those two positions has gone unexplored in news reports about the abortion controversy," Foser concludes (Foser, Media Matters for America, 7/24).~ "Obama Abortion Backtrack Shows He"s All Rhetoric, No Fight," Bonnie Erbe, U.S. News & World Report"s "Thomas Jefferson Street": "[O]ne thing we know will not be incl
Current ads sponsored by the Republican National Committee prod Democrats, while a very large planned campaign by drug makers could take flight soon.
On the second annual World Hepatitis Day, the World Hepatitis Alliance today called on governments not to forget the plight of 500 million people living with hepatitis B and C, as the World Health Assembly postpones discussion of a World Health Organization (WHO) resolution on viral hepatitis - one of the biggest threats to global health.
Mitochondrial diseases disrupt the power generating machinery within cells and increase a person"s susceptibility to bacterial infection, particularly in the lungs or respiratory tract. A new study published in Disease Models & Mechanisms (DMM), shows that infection with the pneumonia causing bacteria Legionella, is facilitated by an increased amount of a signaling protein that is associated with mitochondrial disease.
Using both animal and human cells, Duke University Medical Center scientists have demonstrated that a single lung cell can become one of two very different types of airway cells, which could lead to a better understanding of lung diseases.
Being active at age 5 helps kids stay lean as they age even if they don"t remain as active later in childhood, a new University of Iowa study shows.
Elron Electronic Industries Ltd. (NASDAQ & TASE: ELRN) announced, that further to it previous announcement on July 28, 2009, Medingo Ltd., a group company held 92% by Elron and its subsidiary, RDC - Rafael Development Corporation Ltd., has received formal clearance from the Food and Drug Administration ("FDA"), to market its Solo™ MicroPump Insulin Delivery System in the United States.
The HealthGrades Fourth Annual Bariatric Surgery Trends in American Hospitals Study released today identifies 88 hospitals as "best" performers (five-star rated), with mortality rates, complication rates and patient lengths of stay that are dramatically lower than poorly rated hospitals.
Two articles published this week in the open-access journal PLoS Medicine
Inhibiting an enzyme in the brains of newborns suffering from oxygen and blood flow deprivation stops a type of brain damage that is a leading cause of cerebral palsy, mental retardation and death, according to researchers at Cincinnati Children"s Hospital Medical Center.
The American Hospital Association (AHA) has elected seven new members to its Board of Trustees for terms beginning January 1, 2010. The Board of Trustees is the policy-making body of the AHA and has ultimate authority for the governance and management of its direction and finances.
First, Make No Mistakes The New York Times
Senator John Kerry (D-Mass.), chairman of the Senate Foreign Relations Committee, and ranking member, Senator Richard Lugar (R-Ind.), on Tuesday "introduced a bill to overhaul the U.S. system for providing global development aid," the Boston Globe reports (Smith, 7/29). The legislation was also introduced by Senators Robert Menendez (D-NJ) and Bob Corker (R-Tenn.), according to a release from Menendez"s office (7/28).
Adults who use less salt in their diet can experience a slight reduction in their blood pressure in the medium term. However, whether in the long term this can also reduce the risk of late complications in people with sustained high blood pressure, otherwise known as essential hypertension, and whether in the long term their anti-hypertensive medication can be reduced remains unresolved. This is the conclusion of the Institute for Quality and Efficiency in Health Care (IQWiG) in its final report published in the form of a rapid report on 20 July 2009.
Recycling is a critical component in the process of transmitting information from one neuron to the next, and a large protein called Tweek plays a critical role, said an international consortium of researchers led by Baylor College of Medicine in a report in the current issue of the journal Neuron.
A major clinical challenge is to find the best method to evaluate and to manage the increasing numbers of patients with chronic liver disease. Liver biopsy, due to its risks and limitations, is no longer considered mandatory as the first-line indicator of liver injury, and several markers have been developed as non-invasive alternatives.
Vaccines to protect against sexually transmitted diseases, including HIV and herpes, are being developed and may soon be available to college students. However, limited research has been conducted to determine if students will accept the vaccines once they are available. In a new study, a University of Missouri researcher has found that students who feel invulnerable, or invincible, to physical harm are unlikely to get an HIV vaccine. Alternately, students who feel invulnerable to psychological harm are more likely to get the vaccine.
The Latino/a population in the United States is expected to triple by 2050, according to projections from the U.S. Census Bureau. And along with that growth, says University of Illinois professor Lydia Buki, will come a rise in the number of individuals from that population who are diagnosed with cancer.
Many experimental studies have found that physical exercise can improve cholesterol levels and subsequently decrease the risks of cardiovascular disease; however, few of these studies have included enough participant diversity to provide ethnic breakdowns. Now, a long-term study of over 8,700 middle-aged men and women provides race- and gender- specific data on the cholesterol effects of physical activity, with the interesting result that women, particularly African-American women, experience greater benefits as a result of exercise than men.
A study published online ahead of press in the Gerontology Society of America"s Journal of Gerontology: Medical Sciences reports that the condition of frailty in older adults is associated with a critical mass of abnormal physiological systems, over and above the status of each individual system, and that the relationship is nonlinear. This research is the first evidence that frailty is related to the number of abnormal physiological systems, rather than a specific system abnormality, a chronic disease, or chronological age. It suggests significant alterations in system biology with aging, and underlying frailty. Clinical implications are that prevention and treatment may be more likely to be effective if any given intervention improves multiple systems, not just one.
Older adults who have less strength, poor physical function and low muscle density are at higher risk of being hospitalized compared to adults with more strength and better function. That"s the finding of a new study in the Journal of the American Geriatric Society.
UCSF researchers have identified a new potential drug target for the herpes virus that causes Kaposi"s sarcoma, re-opening the possibility of using the class of drugs called protease inhibitors against the full herpes family of viruses, which for 20 years has been deemed too difficult to attain.
A new approach to statistical analysis may be better suited to study the relationship between higher "dose" of dialysis and survival time for patients with advanced kidney disease, according to an upcoming paper in the Journal of the American Society of Nephrology (JASN).
Doctors" leaders are warning that unless urgent action is taken to plug the gap in the shortage of middle grade doctors, the NHS in Wales could become unsafe both for staff and patients.
Alzheimer"s disease is a progressive neurologic disease of the brain leading to the irreversible loss of neurons and the loss of intellectual abilities, including memory and reasoning, which become severe enough to impede social or occupational functioning. Alzheimer"s disease is also known as simply Alzheimer"s, and Senile Dementia of the Alzheimer Type (SDAT) .
Under economic pressure, states are slashing funding for health services from Connecticut to California. The cuts frustrate providers and lawmakers are looking for ways to limit harm.
South Africa"s Science and Technology Minister Naledi Pandor on Tuesday announced a government-sponsored research initiative that "aims to combat HIV and AIDS through scientific and technological research, the development of new drugs, diagnostic tests and vaccines," SAPA/IOL reports (7/28). "[K]ey focus areas" of the South Africa HIV/AIDS Research and Innovation Platform (SHARP) will be prevention and therapeutics, according to BuaNews (7/28).
An annual report by the Health Council of East Central Florida released on Wednesday said that nearly 800 new cases of HIV were reported in Central Florida in 2008 and blacks and Hispanics remain disproportionately affected, the Orlando Sentinel reports. The report was presented to the Ryan White Planning Council, according to the Sentinel. The report said that there are now more than 4,000 people living with HIV in the area, and another 4,400 living with AIDS. In addition, a majority of the new cases of HIV were among blacks and Hispanics, according to the report (Maza, 7/29). In an interview with the Sentinel, Debbie Tucci, the Orange County Health Department"s HIV/AIDS program coordinator, discussed the findings. She said, "HIV/AIDS is not in the forefront the way it used to be. We"ve been talking about this for a long time, and people just don"t think it"s going to happen to them." She added, "The disease doesn"t care what your race or ethnicity is. Now we target minorities more, and what"s happened is that they"re getting tested more. Prevention strategies are absolutely working. There"s always room for improvement, but we"ve come a long way - especially among minorities" (Maza, 7/30).
The following statistics were released by the Department of Health - Inpatient Waiting Times; Outpatient Waiting Times.
Health plans reiterated their strong support for new market rules and consumer protections to cover all Americans and guarantee coverage for pre-existing conditions.
Migraine headaches are a drain - not only on the estimated 30 million Americans who suffer from them, but on the economy, too. Because pain and other symptoms caused by migraine headaches can be quite severe, it is projected that nearly $13 billion is spent every year in headache treatment and loss of time from work, which no one can afford these days. But according to a new study in Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS), there is hope for severe and frequent migraine sufferers who can"t find relief in conventional remedies.
HHS Secretary Kathleen Sebelius provided the down payment for a nationwide effort to reduce health care associated infections in stand-alone or same-day surgical centers. The first effort will begin later this month in 12 states under provisions of the American Recovery and Reinvestment Act of 2009, administered by the Centers for Medicare & Medicaid Services (CMS).
The Centers for Medicare & Medicaid Services (CMS) announced a proposed 2.2 percent home health market basket update to the home health prospective payment system (HH PPS) rates for calendar year (CY) 2010. Also, as part of ongoing efforts to address potential fraud and abuse with regards to outlier payments under the HH PPS, CMS is proposing modifications to its outlier policy.
A study led by scientists in Austria suggests that kids as young as 9 years old can and should learn how to use CPR (cardiopulmonary
Front-line staff in the nursing and care sector would welcome sensor and robot technology in nursing homes and the homes of elderly people.
Allergan, Inc. (NYSE: AGN) announced that the United States Food and Drug Administration (FDA) has approved ACUVAIL(TM) (ketorolac tromethamine ophthalmic solution) 0.45%, an advanced, preservative-free formulation of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of pain and inflammation following cataract surgery. Cataracts are a leading cause of blindness among older adults and cataract surgery is the most frequently performed surgical procedure in the United States, with more than 3 million procedures performed each year.1
GlaxoSmithKline (GSK) and Genmab A/S (OMX: GEN) announced preliminary top-line results from a Phase III study of ofatumumab administered intravenously for the treatment of rheumatoid arthritis (RA) in patients who had an inadequate response to methotrexate. The study met the primary endpoint, ACR20 at 24 weeks, which indicates a 20 percent or greater improvement in the number of swollen and tender joints, as well as improvements in other disease-activity measures.
"House Speaker Nancy Pelosi is trying to unite her divided caucus around a common enemy - the health insurance industry - previewing an August recess line of attack by Democrats trying to maintain momentum on health care reform," Politico reports. Speaker Nancy Pelosi said yesterday, "They are the villains in this. They have been part of the problem in a major way. They are doing everything in their power to stop a public option from happening, and the public has to know" (Thrush, 7/31).
Health Affairs: Annual Medical Spending Attributable to Obesity: Payer- and Service-Specific Estimates -- Using data from 1998 and 2006 Medical Expenditure Panel Surveys (MEPS) - "a nationally representative survey of the civilian noninstitutionalized population that quantifies a person"s total annual medical spending by type of service and of payment" - the authors estimate the health cost of obesity in the U.S. is $147 billion. "Across all payers, per capita medical spending for the obese is $1,429 higher per year, or roughly 42 percent higher, than for someone of normal weight. In aggregate, the annual medical burden of obesity has increased from 6.5 percent to 9.1 percent of annual medical spending and could be as high as $147 billion per year (in 2008 dollars) based on the NHEA [National Health Expenditure Accounts] estimate," according to the study. In conclusion, the authors write, "The take-home message is that without a strong and sustained reduction in obesity prevalence, obesity will continue to impose major costs on the health system for the foreseeable future. And although health reform may be necessary to address health inequities and rein in rising health spending, real savings are more likely to be achieved through reforms that reduce the prevalence of obesity and related risk factors, including poor diet and inactivity" (7/27).
CNN examines Malawi"s efforts to address its shortage of nurses. Though in the past, health workers "have been lured abroad by the promise of higher wages and better working conditions," the country has succeeded in putting a stop to "its crippling brain drain of nurses" by expanding "educational opportunities for nurses at all levels" and by "paying modestly more money," CNN writes.
Inter Press Service examines several civil society organizations" argument that legislative measures aimed at fighting HIV/AIDS, "hurt more" than they "help." There are 58 countries with laws in place to "prosecute HIV transmission" and 33 others where such legislation is being considered, according to the International Planned Parenthood Federation.
Gastroesophageal reflux diseases , or GERD, affects about 10 million people in the United States, yet the cause and an unexpected increase in its prevalence over the last three decades remains unexplainable. Now, researchers have discovered that GERD is associated with global alteration of the microbiome in the esophagus. The findings, reported in the August 1, 2009 issue of Gastroenterology, may provide for the foundation for further study of the condition as a microecological disease with new treatment possibilities.
The intake of added sugars in the United States is excessive, estimated by the US Department of Agriculture in 1999-2002 as 17% of calories a day. Consuming foods with added sugars displaces nutrient-dense foods in the diet. Reducing or limiting intake of added sugars is an important objective in providing overall dietary guidance. In a study of nearly 30,000 Americans published in the August 2009 issue of the Journal of the American Dietetic Association, researchers report that race/ethnicity, family income and educational status are independently associated with intake of added sugars. Groups with low income and education are particularly vulnerable to eating diets with high added sugars.
In a world first, Melbourne scientists have made a critical breakthrough in understanding the differences in the brains of people with schizophrenia.
UroToday.com - Patients with pain can present with various symptom complexes that include interstitial cystitis, vulvodynia, irritable bowel syndrome, myofascial pain or various causes of dyspareunia but when carefully evaluated, the majority have very similar findings. No matter what their primary complaint might be over 70% of patients will have hypertonic pelvic floor dysfunction and/or pain as well as a component of at least one visceral pain syndrome such as interstitial cystitis (the most common), chronic pelvic pain or irritable bowel syndrome.
UroToday.com - We performed a retrospective review of retroperitoneal lymph node dissection (RPLND) patients with high risk features (>30% embryonal carcinoma, with or without lymphovascular invasion) and compared primary (P-RPLND) versus post-chemotherapy (PC-RPLND) patients. The average percent embryonal carcinoma between P-RPLND vs. PC-RPLND was 75.3 vs. 71.2%, respectively. The average LVI between P-RPLND vs. PC-RPLND was 53.4 vs. 61.4%, respectively.
By searching millions of DNA variations in the genomes of thousands of women with and without ovarian cancer, scientists have discovered a
Major depression and coronary artery disease are only modestly related throughout an individual"s lifetime, but studying how the two interact over time and in twin pairs paints a more complex picture of the associations between the conditions, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals. For example, the association between coronary artery disease onset and major depression risk is much stronger over time than vice versa.
Blue Cross and Blue Shield of Georgia (BCBSGA) announced that it will offer coverage for the administration of the H1N1 (swine flu) vaccine when it becomes commercially available to the general public. The vaccine administration will be covered for members whose benefit plans provide coverage for vaccines.
A carbon nanosensor "electronic nose" first developed by Technion-Israel Institute of Technology researchers to detect cancer from breath samples has been modified to identify chronic renal failure (CRF). The findings, reported in the May 26, 2009 issue of ACS Nano, could lead to a non-invasive and fairly inexpensive way to detect kidney diseases in their earliest and most treatable stages.
UNICEF Executive Director Ann Veneman, who visited Nigeria to launch the country"s first ever National Child Health Week, said an unacceptably high number of children in the country are dying from preventable diseases, and she called on Nigerian government officials to provide integrated healthcare, Xinhua reports (8/3).
Rummaging through a biotechnology company"s chemical closet, Yale University researchers found two molecules that will allow scientists to better study how cells move. The study in the journal Nature, published online Aug. 2, describes how two small molecules discovered by Cytokinetics Inc. block the action of a key complex that directs the assembly of actin filaments, which produce the force to help cells move. The target of these inhibitors is the Arp2/3 complex, a cellular component so vital that cells die without it. This dependence has made it challenging to learn exactly which cellular processes depend upon the complex.
Our cells are controlled by billions of molecular "switches" and chemists at UC Santa Barbara have developed a theory that explains how these molecules work. Their findings may significantly help efforts to build biologically based sensors for the detection of chemicals ranging from drugs to explosives to disease markers.
Whether it"s highlighted in major news headlines about Argentinean affairs and Ponzi schemes, or in personal battles with obesity and drug addiction, individuals regularly succumb to greed, lust and self-destructive behaviors. New research from the Kellogg School of Management examines why this is the case, and demonstrates that individuals believe they have more restraint than they actually possess - ultimately leading to poor decision-making.
Scientists at Leeds and Bradford have discovered a unique "DNA signature" in human sperm, which may act as a key that unlocks an egg"s fertility and triggers new life.
The world"s top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC). As non-small cell lung cancer (NSCLC) is one of the most common types of lung cancer affecting a heterogeneous population, researchers have focused on multi-modality treatment regimens to improve patient outcomes. According to research showcased today at the WCLC, multi-modality, tailored treatment regimens increased patient survival rates compared to single-agent therapies.
Drug companies may exploit new rules to promote their products to the public but present it as mere provision of information, according to an editorial published this week in the Drug and Therapeutics Bulletin (DTB).
Speaker Nancy Pelosi issued the following statement tonight on the vote by the House Energy and Commerce Committee to pass the America"s Affordable Health Choices Act, the third House committee to pass the bill this month. The House Ways and Means Committee and Education and Labor Committee approved the bill earlier this month:
As a fetus does not mount an immune response to maternal proteins that cross the placenta, it has been assumed that a fetus would not reject non-genetically matched blood cells (specifically allogeneic blood cells) if they were transplanted while the fetus was in utero. The hope is that this procedure, which is known as IUHCT, could provide a viable approach for treating congenital blood disorders. However, studies using a mouse model of IUHCT indicate that most fetal recipients of allogeneic blood cells lose their transplanted cells 3-5 weeks after transplantation. Alan Flake and colleagues, at Children"s Hospital of Philadelphia, have now identified an immune mechanism responsible for graft failure in this model of IUHCT. Surprisingly, although fetal immune cells eliminated the transplanted allogeneic blood cells, they were triggered to do so by immune molecules known as alloantibodies that they obtained from their mother"s breast milk. The maternal alloantibodies were produced in response to IUHCT and so the authors conclude that in the absence of either a maternal immune response or transmission of the maternal alloantibodies to the fetus, transplanted blood cells should not be rejected, leaving open the door for IUHCT as a potential clinical strategy.
Bionovo, Inc. (Nasdaq: BNVI) announced positive results from the Phase 1B clinical trial of Bezielle (formerly BZL101), their lead drug candidate for advanced breast cancer. In the trial, Bezielle showed an excellent safety and tolerability profile, and also showed promising indications of efficacy in a difficult-to-treat population.
Kowa Research Institute (KRI) based in Morrisville, NC and Kowa Pharmaceuticals America, Inc. (KPA), a privately-held specialty pharmaceutical company headquartered in Montgomery, AL, announced that the U.S. Food and Drug Administration (FDA) has approved LIVALO(R) (pitavastatin), a potent HMG-CoA reductase inhibitor (statin), for the primary treatment of hypercholesterolemia and combined dyslipidemia.
WHAT: The Nutrient-Rich Foods (NRF) Index is a new, objective, science-based way to measure the total nutritional quality of foods and beverages.
Major groups are promising that the August recess will be filled with advertising wars trying to manage the message of the health care reform debate, Politico reports.
Kaiser A small, rural hospital in Missouri is "rolling the dice" on electronic medical records, its CEO tells the Associated Press. The 47-bed hospitals borrowed nearly $1 million to implement an electronic records system, and that"s on top of a $370,000 operating deficit and staff layoffs. The executives are banking on a government bailout in the form of a "$3 million windfall" of stimulus-funded incentives for hospitals to switch to electronic record-keeping.
"Malaria may have jumped to humans from chimpanzees much as AIDS did, U.S. researchers reported on Monday in a [Proceedings of the National Academy of Sciences] study they hope could help in developing a vaccine against the infection," Reuters reports. The researchers found evidence the Plasmodium falciparum parasite that "causes most cases of malaria is a close genetic relative of a parasite found in chimpanzees," the news service writes (8/4).
The 8th International Conference of Food Science and Technology will bring together more than 100 scientists from China and the United States to present a wealth of information on food quality and safety. Conference sessions will take place in Freeborn Hall on Wednesday and Wellman Hall on Thursday. Both venues are on the UC Davis campus.
Researchers from The University of Texas at Austin will participate in a $3 million, five-year grant from the National Institutes of Health (NIH) to fight influenza and other diseases by creating models that simulate the complex interplay between human behavior and the spread of disease.
SAGE, the world"s fifth largest publisher of academic journals, is pleased to announce the January 2010 launch of a new quarterly journal, Social Psychological and Personality Science (SPPS).
Elevated cholesterol levels in midlife - even levels considered only borderline elevated - significantly increase the risk of Alzheimer"s disease and vascular dementia later in life, according to a new study by researchers at Kaiser Permanente"s Division of Research and the University of Kuopio in Finland. The study appears in the journal Dementia & Geriatric Cognitive Disorders.
Celera Corporation (NASDAQ:CRA) announced yesterday the presentation of data replicating its novel mass spectrometry-based approach to identify and validate circulating protein biomarkers that detect non-small cell lung cancer (NSCLC) in an independent cohort of individuals with lung cancer. This study was performed in collaboration with scientists at NYU Langone Medical Center, NY. A key outcome of the study was the validation of a 9 biomarker immunoassay on a cohort of samples that is enriched for stage I disease, important for screening of early stage disease. The assay detected lung cancer with 92% sensitivity at 93% specificity. The panel also accurately distinguished malignant cases from benign lung disease. The data is being presented at the 13th World Conference on Lung Cancer as part of the International Association for the Study of Lung Cancer (IASLC) in San Francisco, CA.
The results of the first ever silver antimicrobial product trial in a nursing home environment, published in the British Journal of Community Nursing, reveal that levels of potentially deadly bacteria can be dramatically reduced using products treated with silver antimicrobial agents, creating cleaner and safer nursing homes for elderly residents across the UK.
Rib-X Pharmaceuticals, Inc. ("Rib-X" or the "Company"), a development-stage company focused on the discovery, development and commercialization of novel antibiotics for the treatment of antibiotic-resistant infections, today announced positive results from a Phase 2 clinical trial of radezolid in the treatment of community-acquired pneumonia (CAP).
Novavax, Inc. (Nasdaq: NVAX) announced it has manufactured a virus-like particle (VLP) vaccine candidate against the H1N1 pandemic influenza virus under current good-manufacturing practices (cGMP) at its new vaccine manufacturing facility in Rockville, MD. This milestone was accomplished in only 11 weeks after receiving the gene sequence for the H1N1 strain from the U.S. Centers for Disease Control. The Company was able to reach this manufacturing goal by employing proprietary, novel production technology which is not dependent on growing influenza virus in eggs. Chicken eggs are used to produce almost all of the world"s influenza vaccine supply. In addition, Novavax has produced essential reagents for measuring vaccine potency. The Company also has plans to produce additional batches of the pandemic H1N1 VLP vaccine to support human clinical studies and stands ready to assist with additional public health needs in the US as well as foreign countries.
Most people who carry a genetic mutation for a movement disorder called dystonia will never develop symptoms, a phenomenon that has puzzled scientists since the first genetic mutation was identified in the 1990"s. Now, scientists at The Feinstein Institute for Medical Research have figured out why these mutation carriers are protected from symptoms of the disorder they have an additional lesion that evens the score.
A new study raises the possibility that flies and other insects that encounter nanomaterial "hot spots," or spills, near manufacturing facilities in the future could pick up and transport nanoparticles on their bodies, transferring the particles to other flies or habitats in the environment. The study on carbon nanoparticles - barely 1/5,000th the width of a human hair - is scheduled for the Aug. 15 issue of ACS" Environmental Science & Technology, a semi-monthly journal.
The Associated Press reports: "Health care legislation before Congress would allow a new government-sponsored insurance plan to cover abortions, a decision that would affect millions of women and recast federal policy on the divisive issue. Federal funds for abortions are now restricted to cases involving rape, incest or danger to the health of the mother. Abortion opponents say those restrictions should carry over to any health insurance sold through a new marketplace envisioned under the legislation, an exchange where people would choose private coverage or the public plan. Abortion rights supporters say that would have the effect of denying coverage for abortion to millions of women who now have it through workplace insurance and are expected to join the exchange. Advocates on both sides are preparing for a renewed battle over abortion, which could jeopardize political support for President Barack Obama"s health care initiative aimed at covering nearly 50 million uninsured and restraining medical costs" (Alonso-Zaldivar, 8/5).
During a presentation about the Health Agenda for the Americas at the "Seventh
Results of a new study confirm trends that different Hispanic population groups have higher incidence rates of certain cancers and worse cancer outcomes if they live in the United States, than they do if they live in their homelands.
"India has asked UNICEF to stop distributing millions of dollars worth of nutrition aid to children, saying it had been done without permission and at the expense of local food to fight hunger," Reuters reports. Since August 2008, UNICEF has invested about $2.4 million importing "a high energy relief treatment known as "Ready to Use Therapeutic Food" (RUTF)" for children with severe acute malnutrition in the states of Bihar and Madhya Pradesh, according to the news service (Williams, 8/4).
Pfizer will present new data highlighting the company"s commitment to a personalized approach to oncology clinical research, which includes the use of targeted agents in specific patient populations in several advanced and difficult-to-treat cancers. These data will be presented later this month at the 45th Annual American Society of Clinical Oncology (ASCO) annual meeting in Orlando from May 29 to June 2.
Covidien (NYSE: COV), a leading global healthcare products company and recognized innovator in mechanical ventilation and respiratory care devices, announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its Leak Compensation software feature for the Puritan Bennett 840™ ventilator system. This option provides continuous levels of mechanical ventilation to patients requiring respiratory support, regardless of the level of gas leakage that might occur in the circuit or past a patient interface device in the clinical setting.
People living with HIV will benefit from a new test developed by Victoria, Australia scientists that offers a simpler and cheaper way of monitoring the disease in sufferers, Victorian Innovation Minister Gavin Jennings said today.
ViraCor Laboratories, the leader in molecular diagnostic testing for infectious diseases, announced the launch of a new ultrasensitive molecular test to detect JC Virus in cerebral spinal fluid (CSF). The second JCV test to be developed in ViraCor"s laboratories, the ultrasensitive JCV PCR test can accurately detect the virus in a patient sample with as few as 25 viral copies per milliliter of sample.
The word "endocarditis" comes from the word "endocardium". The endocardium is the innermost tunic of the heart, including the endothelium and subendothelial connective tissue; in the atrial wall, smooth muscle and numerous elastic fibers also occur.
Otsuka Pharmaceutical Co., Ltd. (OPC) and Otsuka Pharmaceutical Development and Commercialization, Inc. (OPDC) announced that the U.S. Food and Drug Administration (FDA) has approved SAMSCA(TM) (tolvaptan) as the only oral selective vasopressin antagonist for the treatment of patients with clinically significant hypervolemic and euvolemic hyponatremia (serum sodium less than 125 mEq/L, or less marked hyponatremia that is symptomatic and has resisted correction with fluid restriction) including patients with heart failure, cirrhosis, and the syndrome of inappropriate anti-diuretic hormone (SIADH). Patients requiring urgent treatment to raise serum sodium to prevent or to treat serious neurological deficits should not be treated with SAMSCA. Additionally, it has not been established that raising serum sodium with SAMSCA provides a symptomatic benefit to patients. SAMSCA, an oral vasopressin V2-receptor antagonist, will be commercialized in the United States by Otsuka America Pharmaceutical, Inc. (OAPI).