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Nexavar® In Combination With Chemotherapy Shown To Extend Progression-Free Survival In Patients With Advanced Breast Cancer
Bayer HealthCare AG and Onyx Pharmaceuticals, Inc. announced that their first cooperative group-sponsored randomized Phase II trial in advanced metastatic breast cancer met its primary endpoint of progression-free survival. The study evaluated Nexavar® (sorafenib) tablets in combination with the oral chemotherapeutic, capecitabine, in patients with locally advanced or metastatic HER-2 negative breast cancer. Study findings demonstrated that the median progression-free survival was extended in patients treated with Nexavar and capecitabine compared to patients receiving capecitabine and placebo. These results were statistically significant (p-value = 0.0006). In this trial, the safety and tolerability of the combination was as expected and did not show any new or unexpected toxicities. A complete data analysis from this study is expected to be presented at an upcoming scientific meeting.
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Strategies To Assist Parents Manage Children's Worries Over The H1N1 Flu (Swine Flu)
Acknowledging children"s concerns and reinforcing children"s coping are two key strategies to assist parents in managing their children"s worries over the H1N1 flu (swine flu), reports the Australian Psychological Society (APS).
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Two-thirds Of Publicly-insured Adults Have One Or More Chronic Conditions

Nearly two of every three adult Americans under age 65 who were covered by public insurance from 2005 to 2006 had at least one chronic illness, such as diabetes, heart disease, and kidney disease, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. -- About 57 percent of people with private insurance and 36 percent of the uninsured had one or more chronic ailments, such as diabetes, heart disease, and kidney disease -- People who had two or more chronic illnesses accounted for 45 percent of the publicly insured, 32 percent of the privately insured and 17 percent of the uninsured. -- Health expenditures for treatment of chronic conditions for adults with two or more such conditions averaged $6,455 for people who only had public insurance compared with $1,987 for the uninsured and $3,598 for people with private insurance. -- However, a publicly insured person with two or more chronic illnesses had lower average annual out-of-pocket expenses than a similar uninsured person ($708 vs. $1,040). -- Chronic diseases accounted for 57 percent of medical care spending for adults who only had public insurance, 46 percent for the privately insured, and 47 percent for the uninsured. AHRQ, which is part of the U.S. Department of Health and Human Services, improves the quality, safety, efficiency, and effectiveness of health care for all Americans. The data in this AHRQ News and Numbers summary are taken from the Medical Expenditure Panel Survey (MEPS), a detailed of information on the health services used by Americans, the frequency with which they are used, the cost of those services, and how they are paid. AHRQ


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