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'Taking Up A Dialogue' With The Brain: Letter Decoding From Single-trial Brain Signals
Brain-computer interfaces "translate" what a person is thinking in words or actions. Researchers from Maastricht University in the Netherlands performed functional MRI brain scans on healthy participants, instructing them to "type" by performing mental tasks corresponding to different letters in the English alphabet. Researchers were able to use signals from the participants" brain activation patterns to decode information about the intended letter that a participant was thinking about, and to use this in a conversation with the experimenters without any spoken words. It is hoped that such technology can enable communication with "locked-in" patients or assessment of consciousness in non-responsive patients.
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Sepracor Pharmaceuticals Ltd Withdraws Its Marketing Authorisation Application For Lunivia (eszopiclone)
The European Medicines Agency has been formally notified by Sepracor Pharmaceuticals Ltd of its decision to withdraw its application for a centralised marketing authorisation for the medicine Lunivia (eszopiclone), 2 and 3 mg tablets.
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First Probable Case Of Swine Flu In Wales
A probable case of swine flu in Wales has been identified by microbiology testing.
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The Evolution Of Migraine From Episodic Headache To Chronic Disorder

Patients living with migraine have strong reason for new optimism concerning a positive future. Two review articles and an accompanying editorial, "The Future of Migraine: Beyond Just Another Pill," in the current issue of Mayo Clinic Proceedings, are the basis for an ironic premise. "Migraine is a potentially chronic, progressive disease that substantially affects patients, families, workplaces, and society," according to the editorial written by Roger Cady, M.D., of the Headache Care Center in Springfield, Mo. "Ironically, this is the springboard for renewed optimism of a more positive future for patients living with migraine." Traditionally, Dr. Cady explains, migraine has been considered a pain disorder involving separate or even sporadic episodes. Now, the condition is defined as an all-encompassing and progressive disease that negatively affects all aspects of an individual"s life. Migraine can erode quality of life during what should be a person"s most productive years, according to Dr. Cady. Because migraine patients" quality of life has not improved at a pace with medical advances, research is addressing the overall severity and potential progressive nature of migraine, especially migraine episodes as a forerunner of chronic migraine. According to the three articles, these new insights and understandings are requiring professionals to explore well beyond traditional migraine management. "Understanding migraine as a potentially chronic disease mandates a collaborative health care model with patients and health care professionals working in a partnership toward common therapeutic goals," writes Dr. Cady, specifically intervention and prevention. Physicians and patients must be encouraged to be partners, he says, and evaluation must go far beyond the physician just asking, "How are your migraines?" The models must include an invitation to comprehend and address all migraine-related health issues facing patients, Dr. Cady writes. In addition, understanding the evolutionary "stages" of migraine from sporadic to persistent offers an opportunity to develop new therapies that individualize and personalize care. In the future, successful management of migraine will ideally be measured not by stopping an attack but by overall disease management and prevention, according to the researchers. This new understanding of migraine as a chronic disease offers many challenges and rewards, according to Dr. Cady. "Today, the focus of care is rapidly changing from the event of the migraine to the patient with migraine," he notes. These changes present great promise for patients and health care professionals alike, representing assurances of a better future for patients with migraine, concludes Dr. Cady. John Murphy Mayo Clinic


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