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Evidence For A New Genetic Link To Therapeutic Efficacy For Alzheimer's Disease
Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system diseases, today announced further evidence for genetic interactions impacting the efficacy of the ketogenic compound AC-1202 (Axona(TM)) in Alzheimer"s disease. New data from the company"s previously completed double-blind, placebo-controlled trial in patients with mild-to-moderate Alzheimer"s disease demonstrates an interaction between two genetic markers that strongly influence the therapeutic response in patients. Dr. Samuel Henderson, Executive Director of Research, will present these results at the 2009 International Conference on Alzheimer"s Disease (ICAD) sponsored by the Alzheimer"s Association.
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New Safety Regulations Drive Greater Need For Res And Expertise At Every Stage Of Clinical Development
According to a report issued, drug safety leaders in pharmaceutical and biotechnology companies recognise the need to increase res, either internally or through partnerships, to comply with the safety regulations recently issued by the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMEA). The report - Safety First: The Impact of New Regulations on Clinical Development - is based on a survey of 140 industry safety specialists, including heads of medical, drug safety, pharmacovigilance, and regulatory departments within large and mid-sized pharmaceutical companies and biotech firms. The survey found that more than three-quarters (77%) of respondents believe that new safety regulations have had a considerable impact on the industry as companies implement drug safety regulations throughout the clinical development process.
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Gene Evolution Process Discovered
One of the mechanisms governing how our physical features and behavioural traits have evolved over centuries has been discovered by researchers at the University of Leeds.
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Some Groups Say Iowa HIV Transmission Law Worsens Stigma, Hinders Testing Efforts

Some Iowa groups are concerned that the state"s criminal HIV transmission law adds to the stigma associated with the virus and hampers testing efforts, and are urging lawmakers to revisit the law, the Iowa Independent reports. According to the Independent, criminal transmission of HIV is classified among the second-most serious felonies that can be committed in the state. Those that have been convicted under the law have been sentenced to a few months to several decades in prison. Former state Rep. Ed Fallon (D) who supported the 1998 law, said, "It seems to me that since it is now 11, almost 12, years later, it wouldn"t be [a] bad time to take a look at it again," adding that "surely [there] are some tweaks or changes that the legislature could consider relevant to this law, especially with all the new knowledge we have of the disease" (Waddington, 7/1). This information was reprinted from dailyreports.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily U.S. HIV/AIDS Report, search the archives and sign up for email delivery at dailyreports.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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