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CytRx's Tamibarotene Receives Positive Opinion From The Committee For Orphan Medicinal Products In The European Union For Treatment Of APL
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that its lead drug candidate tamibarotene has received official notification from the Committee for Orphan Medicinal Products (COMP) of the European Medicines Agency (EMEA) that a positive opinion was made regarding the application for orphan medicinal product for the treatment of acute promyelocytic leukemia (APL). The positive opinion of the COMP has now been forwarded to the EU commission for final approval and publication in the community register. This favorable opinion for tamibarotene in the European Union (EU) is in addition to the Orphan Drug Designation for APL and Fast Track Designation for the treatment of adult patients with relapsed or refractory APL following treatment with all-trans retinoic acid (ATRA) and arsenic trioxide granted by the U.S. Food and Drug Administration (FDA) in October 2007.
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Secrets Revealed About How Disease-Causing DNA Mutations Occur
A team of Penn State scientists has shed light on the processes that lead to certain human DNA mutations that are implicated in hundreds of inherited diseases such as tuberous sclerosis and neurofibromatosis type 1. The results one day could influence the way couples who seek to have children receive genetic counseling. The team, led by Kateryna Makova, an associate professor of biology, also includes Erika Kvikstad, a graduate student in the Department of Biology, and Francesca Chiaromonte, an associate professor of statistics. Their findings will be published in the July 2009 issue of the journal Genome Research.
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Few People Changed Their Behaviour In The Early Stages Of The Swine Flu Outbreak
Few people changed their behaviour in the early stages of the swine flu outbreak, finds a study published on bmj.com. But the results do support efforts to inform the public about specific actions that can reduce the risks from swine flu and to communicate about the government"s plans and res.
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Preschoolers' Language Development Is Partly Tied To Their Classmates' Language Skills

Young children learn how to speak and understand language from the words parents speak at home and teachers speak in preschool. A new longitudinal study has found that their preschool classmates also play a part. The study, by researchers at the University of Virginia and Ohio State University, is published in the May/June 2009 issue of the journal Child Development. The researchers took a look at more than 1,800 preschoolers in over 450 pre-kindergarten classrooms in 11 U.S. states. They tested children"s skills in "receptive language" (including their understanding of vocabulary and grammar) and "expressive language" (including their speaking skills, which also involve vocabulary and grammar) in English at the start and end of pre-kindergarten. Children"s abilities to both speak and understand words developed faster when they were with classmates with better language skills. Going to school with children who had better language skills was even more beneficial for children who began preschool with higher language skills, and for those who were in classrooms that were well-managed. "Classmates are an important re for all children, especially for children who begin preschool with higher language skills," suggests Andrew J. Mashburn, a senior research scientist at the University of Virginia and the study"s lead author. "This is likely because these children are better able to capitalize on their peers" skills for learning language. These results also indicate that teachers can promote children"s language development by effectively managing children"s behavior, which creates an environment in which children feel comfortable to converse with and learn language from one another." Given the growing recognition that young children"s language abilities affect their readiness for school and later school success, this study offers ideas for designing and structuring preschool classrooms. The study was funded, in part, by the U.S. Department of Education. Summarized from Child Development, Vol. 80, Issue 3, Peer Effects on Children"s Language Achievement During Pre-Kindergarten by Mashburn, AJ (University of Virginia), Justice, LM (The Ohio State University), and Downer, JT, and Pianta, RC (University of Virginia). Copyright 2009 The Society for Research in Child Development, Inc. All rights reserved. Sarah Hutcheon Society for Research in Child Development


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