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Behavioral Effects Of Addiction Enhanced By Cocaine-Linked Genes
New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior. The study, published by Cell Press in the May 14th issue of the journal Neuron, provides exciting insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction.
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Research Finds Bodybuilders With Similar Body Image Concerns, Whether Or Not They Use Steroids
When it comes to characteristics associated with muscle dysmorphia, there is no difference between bodybuilders who use steroids and those who do not, a University of Arkansas researcher found.
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Rockefeller Foundation Launches $100M 5-Year Initiative To Improve Health Systems In Africa, Asia
The Rockefeller Foundation launched a $100 million, five-year initiative aimed at improving health systems in Asia and Africa, Judith Rodin, the foundation"s president, said in a speech on Wednesday in Nairobi, Kenya, Xinhua reports. The Transforming Health Systems (THS) project will begin with investments in Ghana, Rwanda and Vietnam, and will also support certain regional and global activities (Ooko, 7/1). The goal of THS is to "help countries in Africa and Asia that lack the latest treatments and technology; and where many people are forced to pay their medical bills out of pocket," VOA News writes (DeCapua, 7/1).
Public Health

Henry Ford Hospital Study May Hold Promise For Future Disease Therapies

Linking genetic material microRNAs with cells that regulate the immune system could one day lead to new therapies for treating cancer, infections and autoimmune diseases, according to a Henry Ford Hospital study. Qing-Sheng Mi, M.D., Ph.D., the study"s senior author and director of Henry Ford"s Immunology Program, says their findings are important because it shows for the first time an association between microRNAs and a key subset of immune regulatory cells in the body, natural killer T cells (NKT), which are known to lead to autoimmune diseases and cancer. The study was published June 1 in the Proceedings of the National Academy of Sciences. "While further studies are needed, we believe this provides important insight about how microRNAs can regulate NKT cells, and signals a major step forward in biology science for looking at new therapies for treating some chronic immune disease," Dr. Mi says. MicroRNAs are short strands of genetic material that researchers believe perform a vital role in healthy development by turning off gene activity. NKT cells potent regulators of diverse immune responses in the body. By genetically modifying mice with specific deletion microRNAs in hematopoietic stem cells, Henry Ford researchers showed that the lack of microRNAs can block the development and function of normal NKT cells. If researchers are successful at identifying unique microRNA that specifically regulate NKT cells, Dr. Mi, it could lead to new treatment therapies for some chronic disease. David Olejarz Henry Ford Health System


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