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Singer Elton John Calls For Increased HIV/AIDS Education, Care
Singer Elton John on Tuesday at the 2009 Bio International Convention in Atlanta called for renewed efforts to fight HIV/AIDS, the Atlanta Journal-Constitution reports. John, founder of the Elton John AIDS Foundation, addressed an audience that included CEOs of organizations working to develop HIV/AIDS therapies and vaccines. He called on governments and institutions to increase their focus on education, especially among young people; access to medical treatment; and needle-exchange programs (Poole, Atlanta Journal-Constitution, 5/19)."There are long-standing stereotypes and prejudices that inhibit our efforts to combat AIDS," John said, adding, "I am asking for your leadership." According to John, CDC estimates that one in every three new HIV cases occurs among people younger than age 30, a statistic that he said has not received adequate attention. "It is unfathomable and unconscionable that we are not making a bigger effort to educate this demographic about HIV/AIDS with creative materials and up-to-date information," John said, adding, "Our failure to do so is costing lives" (Turner, AP/PennLive.com, 5/19). John also noted a recent report by the Kaiser Family Foundation, which found that the number of Americans who believe HIV/AIDS is an urgent health problem has declined to 6% currently from 44% in 1995. Bob McNally, CEO of GeoVax Labs, said John"s message is that "just not enough is being done" and that "people continue to die from the disease." He added that John "spurred the audience towards being advocates" (Atlanta Journal-Constitution, 5/20).
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Provectus Completes Patient Accrual In Phase 2 Trial Of PV-10 For Metastatic Melanoma
Provectus Pharmaceuticals, Inc. (OTC BB: PVCT), a development-stage oncology and dermatology biopharmaceutical company has completed patient accrual and initial PV-10 treatment in its Phase 2 trial of PV-10 for metastatic melanoma. The study involved treatment of 80 subjects with Stage III or Stage IV metastatic melanoma.
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UK Health Services Failing 20 Million+ Joint Pain Sufferers
UK health services are failing to meet the needs of millions of chronic joint pain sufferers. More than 80 per cent of chronic back and knee pain sufferers still suffer from pain following treatments recommended by a healthcare professional, according to new research for Bupa.
Oncology

Bisphenol A Exposure Increases Risk Of Abnormal Heart Rhythms In Female Rodents

The chemical bisphenol A, commonly found in many plastic household items, has been linked to yet another health problem in animals - an increased frequency of arrhythmias, or heartbeat irregularities, a new study found. The results, seen only in females, will be presented Saturday at The Endocrine Society"s 91st Annual Meeting in Washington, D.C. Past animal studies show that bisphenol A, or BPA, can have harmful effects on the reproductive, nervous and immune systems. Also, a study in humans reported last year found an increased prevalence of cardiovascular disease in people with high levels of BPA in the urine. However, the effects of BPA on the heart are unknown, said study co-author Scott Belcher, PhD, associate professor in the University of Cincinnati"s Department of Pharmacology and Cell Biophysics. In the new study, funded by the National Institutes of Health, the University of Cincinnati researchers found that low-dose BPA and estrogen can act alone or in combination to increase harmful arrhythmias in female rats and mice. Because BPA has properties similar to the main female hormone estrogen, it is considered an "environmental estrogen." Mice and rats in the study had normal heart rhythms at baseline, before administration of BPA or estrogen (estradiol), Belcher said. The investigators studied heart rhythms in both the working heart and in cultured heart muscle cells. In both models, exposure to BPA increased the frequency of arrhythmias, compared to baseline, in females but not in male animals, the authors found. Administration of estrogen alone also increased the frequency of arrhythmias in females. Arrhythmias were most frequent in the female rats and mice when they received both BPA and estrogen, at levels normally found in female humans. "We have identified a new possible risk for female heart health, caused by increased levels of estrogens in the body and exposure to the environmental estrogen BPA," Belcher said. BPA is found in polycarbonate-plastic baby bottles, refillable water bottles and food containers as well as the linings of metal food cans. Last year the U.S. Food and Drug Administration said more research on the safety of BPA is needed. Arrhythmias occur when the heart beats too slowly or too fast or when it skips heartbeats. These heart rhythm irregularities can cause fatigue, lightheadedness, fainting or sudden cardiac death. If a fast heart rate affects the heart"s ability to pump, it can cause a heart attack. The study"s lead author, Hong-Sheng Wang, PhD, assistant professor at the University of Cincinnati, will present the results. Aaron Lohr The Endocrine Society


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